Literature DB >> 11306140

The levels of tetrodotoxin and its analogue 6-epitetrodotoxin in the red-spotted newt, Notophthalmus viridescens.

M Yotsu-Yamashita1, D Mebs.   

Abstract

Tetrodotoxin (TTX) and its analogue 6-epiTTX were detected in 11-12 specimens of the red-spotted newt, Notophthalmus viridescens, by a post-column fluorescent-HPLC system and by LC/MS in selected ion monitoring mode. TTX levels varied considerably among individuals from low (less than 0.15 microg TTX/g newt) to high concentrations (23.5 microg TTX/g newt), while 6-epiTTX was found to be a minor constituent in all specimens.

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Year:  2001        PMID: 11306140     DOI: 10.1016/s0041-0101(00)00263-4

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  11 in total

1.  Parallel arms races between garter snakes and newts involving tetrodotoxin as the phenotypic interface of coevolution.

Authors:  Edmund D Brodie; Chris R Feldman; Charles T Hanifin; Jeffrey E Motychak; Daniel G Mulcahy; Becky L Williams; Edmund D Brodie
Journal:  J Chem Ecol       Date:  2005-02       Impact factor: 2.626

2.  The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: a potent sodium-channel blocker.

Authors:  Mari Yotsu-Yamashita; Yong H Kim; Samuel C Dudley; Gaurav Choudhary; Arnold Pfahnl; Yasukatsu Oshima; John W Daly
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-22       Impact factor: 11.205

Review 3.  The chemical and evolutionary ecology of tetrodotoxin (TTX) toxicity in terrestrial vertebrates.

Authors:  Charles T Hanifin
Journal:  Mar Drugs       Date:  2010-03-10       Impact factor: 5.118

4.  Tetrodotoxin levels in eggs of the rough-skin newt, Taricha granulosa, are correlated with female toxicity.

Authors:  Charles T Hanifin; Edmund D Brodie; Edmund D Brodie
Journal:  J Chem Ecol       Date:  2003-08       Impact factor: 2.626

5.  Chemical defense of the eastern newt (Notophthalmus viridescens): variation in efficiency against different consumers and in different habitats.

Authors:  Zachary H Marion; Mark E Hay
Journal:  PLoS One       Date:  2011-12-02       Impact factor: 3.240

Review 6.  Tetrodotoxin: chemistry, toxicity, source, distribution and detection.

Authors:  Vaishali Bane; Mary Lehane; Madhurima Dikshit; Alan O'Riordan; Ambrose Furey
Journal:  Toxins (Basel)       Date:  2014-02-21       Impact factor: 4.546

7.  Parallel evolution of tetrodotoxin resistance in three voltage-gated sodium channel genes in the garter snake Thamnophis sirtalis.

Authors:  Joel W McGlothlin; John P Chuckalovcak; Daniel E Janes; Scott V Edwards; Chris R Feldman; Edmund D Brodie; Michael E Pfrender; Edmund D Brodie
Journal:  Mol Biol Evol       Date:  2014-08-18       Impact factor: 16.240

8.  Phenotypic mismatches reveal escape from arms-race coevolution.

Authors:  Charles T Hanifin; Edmund D Brodie; Edmund D Brodie
Journal:  PLoS Biol       Date:  2008-03-11       Impact factor: 8.029

Review 9.  Tetrodotoxin--distribution and accumulation in aquatic organisms, and cases of human intoxication.

Authors:  Tamao Noguchi; Osamu Arakawa
Journal:  Mar Drugs       Date:  2008-05-28       Impact factor: 5.118

Review 10.  Batrachochytrium salamandrivorans: The North American Response and a Call for Action.

Authors:  Matthew J Gray; James P Lewis; Priya Nanjappa; Blake Klocke; Frank Pasmans; An Martel; Craig Stephen; Gabriela Parra Olea; Scott A Smith; Allison Sacerdote-Velat; Michelle R Christman; Jennifer M Williams; Deanna H Olson
Journal:  PLoS Pathog       Date:  2015-12-10       Impact factor: 6.823

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