Literature DB >> 11305099

Identification of Ras-regulated genes by representational difference analysis.

J M Shields1, C J Der, S Powers.   

Abstract

In conclusion, RDA provides a fast, technically simple, and inexpensive way to characterize genes aberrantly expressed due to Ras transformation. The identification and characterization of these genes may provide insight not only into the mechanism by which Ras causes transformation, but also may identify novel targets for rational drug design and development of anticancer drugs.

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Year:  2001        PMID： 11305099     DOI： 10.1016/s0076-6879(01)32205-x

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  2 in total

1.  Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.

Authors:  Janiel M Shields; Heena Mehta; Kevin Pruitt; Channing J Der
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

2.  Gene expression profiling by DNA microarray analysis in mouse embryonic fibroblasts transformed by rasV12 mutated protein and the E1A oncogene.

Authors:  Sophie Vasseur; Cédric Malicet; Ezequiel L Calvo; Claude Labrie; Patrice Berthezene; Jean Charles Dagorn; Juan Lucio Iovanna
Journal:  Mol Cancer       Date:  2003-03-19       Impact factor: 27.401
  2 in total

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