Literature DB >> 11304842

Heparin induced thrombocytopenia thrombosis (HIT/T) syndrome: diagnosis and treatment.

T P Baglin1.   

Abstract

Heparin induced thrombocytopenia thrombosis (HIT/T) is associated with a high morbidity and mortality. Diagnosis is essentially clinical and negative results of laboratory assays do not exclude the diagnosis. Treatment involves stopping all heparin immediately and giving an alternative thrombin inhibitor. The adoption of low molecular weight heparins is one reason for the reduced incidence of this disease in recent years.

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Year:  2001        PMID： 11304842      PMCID： PMC1731401          DOI： 10.1136/jcp.54.4.272

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  26 in total

Review 1.  Anticoagulation with Novastan (argatroban) in patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome.

Authors:  B E Lewis; J M Walenga; D E Wallis
Journal:  Semin Thromb Hemost       Date:  1997       Impact factor: 4.180

2.  Clinical experience with combined treatment of thrombin inhibitors and GPIIb/IIIa inhibitors in patients with HIT.

Authors:  J M Walenga; W P Jeske; D E Wallis; M Bakhos; B E Lewis; F Leya; J Fareed
Journal:  Semin Thromb Hemost       Date:  1999       Impact factor: 4.180

Review 3.  Heparin-induced thrombocytopenia.

Authors:  B H Chong
Journal:  Br J Haematol       Date:  1995-03       Impact factor: 6.998

4.  A diagnostic test for heparin-induced thrombocytopenia: detection of platelet microparticles using flow cytometry.

Authors:  D H Lee; T E Warkentin; G A Denomme; C P Hayward; J G Kelton
Journal:  Br J Haematol       Date:  1996-12       Impact factor: 6.998

5.  Use of enoxaparin in patients with heparin-induced thrombocytopenia syndrome.

Authors:  M M Slocum; J G Adams; R Teel; D P Spadone; D Silver
Journal:  J Vasc Surg       Date:  1996-05       Impact factor: 4.268

6.  The clinical usefulness of the platelet aggregation test for the diagnosis of heparin-induced thrombocytopenia.

Authors:  B H Chong; J Burgess; F Ismail
Journal:  Thromb Haemost       Date:  1993-04-01       Impact factor: 5.249

7.  Laboratory diagnosis of heparin-associated thrombocytopenia and comparison of platelet aggregation test, heparin-induced platelet activation test, and platelet factor 4/heparin enzyme-linked immunosorbent assay.

Authors:  A Greinacher; J Amiral; V Dummel; A Vissac; V Kiefel; C Mueller-Eckhardt
Journal:  Transfusion       Date:  1994-05       Impact factor: 3.157

8.  Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with orgaran (Org 10172)

Authors:  H N Magnani
Journal:  Thromb Haemost       Date:  1993-10-18       Impact factor: 5.249

9.  Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia.

Authors:  T E Warkentin; C P Hayward; L K Boshkov; A V Santos; J A Sheppard; A P Bode; J G Kelton
Journal:  Blood       Date:  1994-12-01       Impact factor: 22.113

10.  Platelet aggregation in response to four low molecular weight heparins and the heparinoid ORG 10172 in patients with heparin-induced thrombocytopenia.

Authors:  D M Keeling; E M Richards; T P Baglin
Journal:  Br J Haematol       Date:  1994-02       Impact factor: 6.998
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  7 in total

1.  Recurrent venous thrombosis following free flap surgery: The role of heparin-induced thrombocytopenia.

Authors:  Andreas Nikolis; Apostolos Christopoulos; Michel Saint-Cyr; Carlos Cordoba; Louis Guertin; Patrick G Harris
Journal:  Can J Plast Surg       Date:  2003

Review 2.  [Thrombocytopathy and blood complications in uremia].

Authors:  Walter H Hörl
Journal:  Wien Klin Wochenschr       Date:  2006-04       Impact factor: 1.704

Review 3.  Cardiopulmonary bypass in patients with pre-existing coagulopathy.

Authors:  William DeBois; Junli Liu; Leonard Lee; Leonard Girardi; Wilson Ko; Anthony Tortolani; Karl Krieger; O Wayne Isom
Journal:  J Extra Corpor Technol       Date:  2005-03

4.  Catastrophic heparin-induced thrombocytopenia/thrombosis syndrome related to the use of a Port-A-Cath in a breast cancer patient receiving chemotherapy.

Authors:  Ming-Shen Dai; An-Tie Hsieh; Tsu-Yi Chao
Journal:  Support Care Cancer       Date:  2004-04-28       Impact factor: 3.603

5.  Heparin-induced thrombocytopenia presenting as splenic hemorrhage following cardiac surgery: a case report.

Authors:  Joseph Ferry; Samuel Youssef; Pierce Wu; Livia Hegerova
Journal:  Thromb J       Date:  2021-01-19

6.  Renal replacement therapy for acute renal failure in children: European guidelines.

Authors:  Vladimirs Strazdins; Alan R Watson; Ben Harvey
Journal:  Pediatr Nephrol       Date:  2003-12-18       Impact factor: 3.714

7.  To clot or not to clot? Ad is the question-Insights on mechanisms related to vaccine-induced thrombotic thrombocytopenia.

Authors:  Maha Othman; Alexander T Baker; Elena Gupalo; Abdelrahman Elsebaie; Carly M Bliss; Matthew T Rondina; David Lillicrap; Alan L Parker
Journal:  J Thromb Haemost       Date:  2021-08-23       Impact factor: 16.036
  7 in total

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