Literature DB >> 11304120

Allosteric behavior in cytochrome p450-dependent in vitro drug-drug interactions: a prospective based on conformational dynamics.

W M Atkins1, R W Wang, A Y Lu.   

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Year:  2001        PMID: 11304120     DOI: 10.1021/tx0002132

Source DB:  PubMed          Journal:  Chem Res Toxicol        ISSN: 0893-228X            Impact factor:   3.739


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  29 in total

Review 1.  Allosteric P450 mechanisms: multiple binding sites, multiple conformers or both?

Authors:  Dmitri R Davydov; James R Halpert
Journal:  Expert Opin Drug Metab Toxicol       Date:  2008-12       Impact factor: 4.481

2.  Role of subunit interactions in P450 oligomers in the loss of homotropic cooperativity in the cytochrome P450 3A4 mutant L211F/D214E/F304W.

Authors:  Harshica Fernando; Dmitri R Davydov; Christopher C Chin; James R Halpert
Journal:  Arch Biochem Biophys       Date:  2007-01-12       Impact factor: 4.013

3.  Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates.

Authors:  Jed N Lampe; Relly Brandman; Santhosh Sivaramakrishnan; Paul R Ortiz de Montellano
Journal:  J Biol Chem       Date:  2010-01-22       Impact factor: 5.157

Review 4.  Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand Interactions.

Authors:  Irina F Sevrioukova; Thomas L Poulos
Journal:  Adv Exp Med Biol       Date:  2015       Impact factor: 2.622

5.  Correction to "Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213".

Authors:  Ilia G Denisov; Yelena V Grinkova; Prithviraj Nandigrami; Mrinal Shekhar; Emad Tajkhorshid; Stephen G Sligar
Journal:  Biochemistry       Date:  2019-06-06       Impact factor: 3.162

Review 6.  A novel type of allosteric regulation: functional cooperativity in monomeric proteins.

Authors:  Ilia G Denisov; Stephen G Sligar
Journal:  Arch Biochem Biophys       Date:  2012-01-08       Impact factor: 4.013

7.  Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probe.

Authors:  Tamara N Tsalkova; Nadezhda Y Davydova; James R Halpert; Dmitri R Davydov
Journal:  Biochemistry       Date:  2007-01-09       Impact factor: 3.162

8.  Resolution of two substrate-binding sites in an engineered cytochrome P450eryF bearing a fluorescent probe.

Authors:  Dmitri R Davydov; Alexandra E Botchkareva; Nadezhda E Davydova; James R Halpert
Journal:  Biophys J       Date:  2005-04-15       Impact factor: 4.033

9.  Effect of glutathione on homo- and heterotropic cooperativity in cytochrome P450 3A4.

Authors:  Dmitri R Davydov; Nadezhda Y Davydova; Tamara N Tsalkova; James R Halpert
Journal:  Arch Biochem Biophys       Date:  2008-01-11       Impact factor: 4.013

10.  Experimental approaches to evaluate activities of cytochromes P450 3A.

Authors:  Lucie Bořek-Dohalská; Petr Hodek; Jiří Hudeček; Marie Stiborová
Journal:  Interdiscip Toxicol       Date:  2008-09
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