Literature DB >> 11303763

Intracellular processing of aggregated tau differs between corticobasal degeneration and progressive supranuclear palsy.

T Arai1, K Ikeda, H Akiyama, K Tsuchiya, S Yagishita, J Takamatsu.   

Abstract

Corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) are sporadic neurodegenerative diseases with intracytoplasmic aggregates of the microtubule-associated protein, tau, in neurons and glial cells. Immunoblot analysis of detergent-insoluble brain extracts of patients with CBD and PSP shows distinctive patterns of tau fragments. These results suggest differing intracellular processing of aggregated tau in these two diseases despite an identical composition of tau isoforms. Such biochemical differences may be related to the neuropathological features of these diseases.

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Year:  2001        PMID： 11303763     DOI： 10.1097/00001756-200104170-00014

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  7 in total

1.  Sleep Disorders in Atypical Parkinsonism.

Authors:  Sabra M Abbott; Aleksandar Videnovic
Journal:  Mov Disord Clin Pract       Date:  2014-06-01

Review 2.  Corticobasal degeneration: a pathologically distinct 4R tauopathy.

Authors:  Naomi Kouri; Jennifer L Whitwell; Keith A Josephs; Rosa Rademakers; Dennis W Dickson
Journal:  Nat Rev Neurol       Date:  2011-04-12       Impact factor: 42.937

Review 3.  Progressive supranuclear palsy.

Authors:  K Tawana; D B Ramsden
Journal:  Mol Pathol       Date:  2001-12

4.  Exposure of the Amino Terminus of Tau Is a Pathological Event in Multiple Tauopathies.

Authors:  Benjamin Combs; Nicholas M Kanaan
Journal:  Am J Pathol       Date:  2017-04-14       Impact factor: 4.307

5.  SUMO1 Modification of Tau in Progressive Supranuclear Palsy.

Authors:  Hironori Takamura; Yoshiaki Nakayama; Hidefumi Ito; Taiichi Katayama; Paul E Fraser; Shinsuke Matsuzaki
Journal:  Mol Neurobiol       Date:  2022-05-14       Impact factor: 5.682

6.  Characterization of tau oligomeric seeds in progressive supranuclear palsy.

Authors:  Julia E Gerson; Urmi Sengupta; Cristian A Lasagna-Reeves; Marcos J Guerrero-Muñoz; Juan Troncoso; Rakez Kayed
Journal:  Acta Neuropathol Commun       Date:  2014-06-14       Impact factor: 7.801

7.  A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.

Authors:  Celeste M Karch; Aimee W Kao; Anna Karydas; Khadijah Onanuga; Rita Martinez; Andrea Argouarch; Chao Wang; Cindy Huang; Peter Dongmin Sohn; Kathryn R Bowles; Salvatore Spina; M Catarina Silva; Jacob A Marsh; Simon Hsu; Derian A Pugh; Nupur Ghoshal; Joanne Norton; Yadong Huang; Suzee E Lee; William W Seeley; Panagiotis Theofilas; Lea T Grinberg; Fermin Moreno; Kathryn McIlroy; Bradley F Boeve; Nigel J Cairns; John F Crary; Stephen J Haggarty; Justin K Ichida; Kenneth S Kosik; Bruce L Miller; Li Gan; Alison M Goate; Sally Temple
Journal:  Stem Cell Reports       Date:  2019-10-17       Impact factor: 7.294
  7 in total

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