Literature DB >> 11302728

Human BTR1, a new bicarbonate transporter superfamily member and human AE4 from kidney.

M D Parker1, E P Ourmozdi, M J Tanner.   

Abstract

We report the cloning, characterization, and chromosomal localization of two novel human members of the bicarbonate transporter superfamily, BTR1 (Bicarbonate Transporter Related protein-1) and AE4 (Anion Exchange protein 4). BTR1 is a novel mammalian protein. The BTR1 gene maps to chromosome 20p12 and encodes a 100 kDa protein predominantly expressed in the kidney, salivary glands, testis, thyroid glands, and trachea. The AE4 gene maps to chromosome 5q23-31 and encodes a 104 kDa protein expressed mainly in the kidney. Human AE4 shares 84% identity with the recently reported rabbit AE4, a sodium independent, Cl(-)/HCO(-)(3) exchanger located on the apical membrane of beta-intercalated kidney cells. Copyright 2001 Academic Press.

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Year:  2001        PMID： 11302728     DOI： 10.1006/bbrc.2001.4692

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  45 in total

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Review 2.  Molecular mechanisms of electrogenic sodium bicarbonate cotransport: structural and equilibrium thermodynamic considerations.

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Journal:  J Membr Biol       Date:  2004-01-15       Impact factor: 1.843

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4.  Transport of H2S and HS(-) across the human red blood cell membrane: rapid H2S diffusion and AE1-mediated Cl(-)/HS(-) exchange.

Authors:  Michael L Jennings
Journal:  Am J Physiol Cell Physiol       Date:  2013-07-17       Impact factor: 4.249

5.  SLC4A11 prevents osmotic imbalance leading to corneal endothelial dystrophy, deafness, and polyuria.

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6.  Regulation of AE2-mediated Cl- transport by intracellular or by extracellular pH requires highly conserved amino acid residues of the AE2 NH2-terminal cytoplasmic domain.

Authors:  A K Stewart; M N Chernova; B E Shmukler; S Wilhelm; S L Alper
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Review 7.  The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transporters.

Authors:  Mark D Parker; Walter F Boron
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8.  Whole exome sequence analysis of Peters anomaly.

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9.  SLC4A11 function: evidence for H+(OH-) and NH3-H+ transport.

Authors:  Liyo Kao; Rustam Azimov; Xuesi M Shao; Natalia Abuladze; Debra Newman; Hristina Zhekova; Sergei Noskov; Alexander Pushkin; Ira Kurtz
Journal:  Am J Physiol Cell Physiol       Date:  2019-11-27       Impact factor: 4.249

10.  Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNS.

Authors:  L-M Chen; M L Kelly; M D Parker; P Bouyer; H S Gill; J M Felie; B A Davis; W F Boron
Journal:  Neuroscience       Date:  2008-02-21       Impact factor: 3.590
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