| Literature DB >> 11301868 |
C Ito, M Itoigawa, M Ogata, X Y Mou, H Tokuda, H Nishino, H Furukawa.
Abstract
Seven lignans (2-8) isolated from the seeds of Hernandia ovigera L. (Hernandiaceae) were tested for their inhibitory effects on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoylphorbol 13-acetate in Raji cells. Using a primary screening test, all the lignans showed inhibitory activity with IC50 470-590 mol ratio/32 pmol TPA. The data demonstrated that these lignans might be valuable anti-tumor-promoters.Entities:
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Year: 2001 PMID： 11301868 DOI： 10.1055/s-2001-11501
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352