| Literature DB >> 11301863 |
G Romussi1, G Ciarallo, A Bisio, N Fontana, F De Simone, N De Tommasi, N Mascolo, L Pinto.
Abstract
From the leaf surface exudate of the aerial parts of Salvia cinnabarina a new secoisopimarane diterpenoid with a non-specific spasmolytic activity on histamine-, acetylcholine-, and barium chloride-induced contractions in the isolated guinea-pig ileum was obtained. The IC50 value obtained was comparable with that obtained for papaverine. The structure of 3,4-secoisopimara-4(18),7,15-triene-3-oic acid was established by 1D and 2D NMR spectroscopic techniques.Entities:
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Year: 2001 PMID： 11301863 DOI： 10.1055/s-2001-11511
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352