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Literature DB >> 11301264

Growth control: invertebrate insulin surprises!

Abstract

Recent work on Drosophila has provided new insights into how insulin signalling - conserved in mammals, flies and worms - regulates growth and cell division during development. Invertebrates have been found to possess more insulin-like ligands than predicted, some of which behave as receptor antagonists.

Entities: Gene Species

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Year: 2001 PMID： 11301264 DOI： 10.1016/s0960-9822(01)00107-5

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

16 in total

1. Bombyxin is a growth factor for wing imaginal disks in Lepidoptera.

Authors: H Frederik Nijhout; Laura W Grunert
Journal: Proc Natl Acad Sci U S A Date: 2002-11-12 Impact factor: 11.205

2. Dachshund homologues play a conserved role in islet cell development.

Authors: Anna Kalousova; Anastasia Mavropoulos; Bruce A Adams; Nada Nekrep; Zhongmei Li; Stephan Krauss; Didier Y Stainier; Michael S German
Journal: Dev Biol Date: 2010-09-30 Impact factor: 3.582

Review 3. Cell death in the nervous system: lessons from insulin and insulin-like growth factors.

Authors: Isabel Varela-Nieto; Enrique J de la Rosa; Ana I Valenciano; Yolanda León
Journal: Mol Neurobiol Date: 2003-08 Impact factor: 5.590

4. Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.

Authors: Jose M Lizcano; Saif Alrubaie; Agnieszka Kieloch; Maria Deak; Sally J Leevers; Dario R Alessi
Journal: Biochem J Date: 2003-09-01 Impact factor: 3.857

5. Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells.

Authors: G Bikopoulos; R B Ceddia; G Sweeney; A J Hilliker
Journal: Cell Prolif Date: 2004-08 Impact factor: 6.831

Growth control: invertebrate insulin surprises!

1. Bombyxin is a growth factor for wing imaginal disks in Lepidoptera.

2. Dachshund homologues play a conserved role in islet cell development.

Review 3. Cell death in the nervous system: lessons from insulin and insulin-like growth factors.

4. Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.

5. Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells.

6. Germ band retraction as a landmark in glucose metabolism during Aedes aegypti embryogenesis.

7. Deletion of Drosophila insulin-like peptides causes growth defects and metabolic abnormalities.

8. An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegypti.

9. Unusual duplication of the insulin-like receptor in the crustacean Daphnia pulex.

10. Functional protein divergence in the evolution of Homo sapiens.