Literature DB >> 11299788

Expression of laminin in metastatic melanoma cell lines with different metastatic potential.

H B Chen1, L Chen, J K Zhung, V W Chow, B Q Wu, Z H Wang, S B Cheng, E C Chew.   

Abstract

Cancer metastasis is a complex multi-step process in which tumor cells leave the primary site and develop a secondary tumor in distant organs. Laminin plays an important role in this process. The expression of laminin in four melanoma cell lines with different metastatic potentials was investigated by immunohistochemistry, immunogold electron microscopy and Western blotting. Our results showed that the expression of endogenous laminin and the percentage of the positive cells are higher with increased metastatic potentials. It is, thus, suggested that endogenous laminin may contribute to the different metastatic properties in the melanoma cell line.

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Year:  2001        PMID： 11299788

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  4 in total

1.  Melanoma spheroid formation involves laminin-associated vasculogenic mimicry.

Authors:  Allison R Larson; Chung-Wei Lee; Cecilia Lezcano; Qian Zhan; John Huang; Andrew H Fischer; George F Murphy
Journal:  Am J Pathol       Date:  2014-01       Impact factor: 4.307

2.  Tumor cell plasticity in uveal melanoma: microenvironment directed dampening of the invasive and metastatic genotype and phenotype accompanies the generation of vasculogenic mimicry patterns.

Authors:  Robert Folberg; Zarema Arbieva; Jonas Moses; Amin Hayee; Tone Sandal; Shrihari Kadkol; Amy Y Lin; Klara Valyi-Nagy; Suman Setty; Lu Leach; Patricia Chévez-Barrios; Peter Larsen; Dibyen Majumdar; Jacob Pe'er; Andrew J Maniotis
Journal:  Am J Pathol       Date:  2006-10       Impact factor: 4.307

3.  Clinical significance of serum laminin and type-IV collagen levels in cutaneous melanoma patients.

Authors:  Faruk Tas; Elif Bilgin; Senem Karabulut; Derya Duranyildiz
Journal:  Mol Clin Oncol       Date:  2016-04-25

4.  Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS.

Authors:  Ken Flanagan; Kent Fitzgerald; Jeanne Baker; Karin Regnstrom; Shyra Gardai; Frederique Bard; Simonetta Mocci; Pui Seto; Monica You; Catherine Larochelle; Alexandre Prat; Samuel Chow; Lauri Li; Chris Vandevert; Wagner Zago; Carlos Lorenzana; Christopher Nishioka; Jennifer Hoffman; Raquel Botelho; Christopher Willits; Kevin Tanaka; Jennifer Johnston; Ted Yednock
Journal:  PLoS One       Date:  2012-07-06       Impact factor: 3.240
  4 in total

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