Literature DB >> 11299746

In vitro biological activity of prenylflavanones.

Y Shirataki1, N Motohashi, S Tani, H Sakagami, K Satoh, H Nakashima, S K Mahapatra, K Ganguly, S G Dastidar, A N Chakrabarty.   

Abstract

The biological activity of ten prenylflavanones purified from Sophora tomentosa L., and Sophora moorcroftiana Benth. ex Baker (Leguminosae) was investigated. The flavanones with prenyl-, lavandulyl- or geranyl groups on A ring, and two bioactive flavonostilbenes on ring B and stilbene (resveratrol) showed tumor-specific cytotoxic activity, antimicrobial activity, and anti-HIV activity, radical generation, and O2- scavenging activity. There was a positive relationship between radical generation and O2- scavenging activity in these prenylflavanones. These data suggest the medicinal significance of prenylflavanones.

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Year:  2001        PMID： 11299746

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  6 in total

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Review 5.  Prenylated Flavonoids in Topical Infections and Wound Healing.

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Journal:  Molecules       Date:  2022-07-13       Impact factor: 4.927

6.  Nymphaeol-A Isolated from Okinawan Propolis Suppresses Angiogenesis and Induces Caspase-Dependent Apoptosis via Inactivation of Survival Signals.

Authors:  Ikumi Tsuchiya; Takahiro Hosoya; Motoko Ushida; Kazuhiro Kunimasa; Toshiro Ohta; Shigenori Kumazawa
Journal:  Evid Based Complement Alternat Med       Date:  2013-04-24       Impact factor: 2.629
  6 in total

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