Literature DB >> 11299101

Urinary tract infection associated with ureteral stents in renal transplantation.

David B. Glazier1, Martin G. Jacobs, Neil W. Lyman, Mathew I. S. Whang, Einat Manor, Shamkant P. Mulgaonkar.   

Abstract

OBJECTIVES: In the mid 1980s, ureteral stents were used in renal transplantation when ureteral injury had occurred. Subsequently, it was shown that routine ureteral stent placement at the time of transplantation reduced urological complications. We carried out a chart review on renal transplant patients and noted which patients developed urinary tract infections (UTIs) with stents in place, and whether these infections ultimately affected transplant outcome. We sought to distinguish subgroups of patients who were more likely to develop infection and to identify the optimum time for stent removal. PATIENTS AND METHODS: We performed a retrospective chart review of 213 patients who underwent renal transplantation in 1994 and 1995. Adequate follow-up information was available on 167 patients with intraoperative stent placement. Of these 167 patients, 4 patients expired and 8 required transplant nephrectomy due to complications unrelated to the stent.
RESULTS: In total, 35 patients (22.6%) developed a post-operative UTI. One infection occurred during the first week following transplant, 3 developed within 2 weeks, and importantly, the remaining 32 infections occurred more than 2 weeks after transplant. An increase in infections in diabetics (25.7%) as compared to other transplant recipients (20.2%) was noted. Patients with cadaveric renal transplants are also at higher risk of UTI (24%) compared to those with living related donors (15%).
CONCLUSION: The use of ureteral stents is safe, but is associated with a UTI rate of 22.6%. To reduce infection rates, we recommend stent removal within 14 days and earlier if possible, particularly in diabetic patients who have received a cadaveric renal transplant.

Entities:  

Year:  1998        PMID: 11299101

Source DB:  PubMed          Journal:  Can J Urol        ISSN: 1195-9479            Impact factor:   1.344


  7 in total

1.  Urinary tract infections in renal transplant recipients.

Authors:  George Alangaden
Journal:  Curr Infect Dis Rep       Date:  2007-11       Impact factor: 3.725

2.  Recurrent urinary tract infections in kidney transplant recipients during the first-year influence long-term graft function: a single-center retrospective cohort study.

Authors:  Francesco Pesce; Marida Martino; Marco Fiorentino; Tiziana Rollo; Simona Simone; Pasquale Gallo; Giovanni Stallone; Giuseppe Grandaliano; Antonio Schena; Marcella Margiotta; Donata Mininni; Rita Palieri; Giuseppe Lucarelli; Michele Battaglia; Loreto Gesualdo; Giuseppe Castellano
Journal:  J Nephrol       Date:  2019-01-30       Impact factor: 3.902

3.  Lower risk of urinary tract infection with low-dose trimethoprim/sulfamethoxazole compared to dapsone prophylaxis in older renal transplant patients on a rapid steroid-withdrawal immunosuppression regimen.

Authors:  Jeffrey Allen Giullian; Kerri Cavanaugh; Heidi Schaefer
Journal:  Clin Transplant       Date:  2010 Sep-Oct       Impact factor: 2.863

4.  Epidemiology and outcomes of carbapenem-resistant Klebsiella pneumoniae bacteriuria in kidney transplant recipients.

Authors:  S M Pouch; C J Kubin; M J Satlin; D S Tsapepas; J R Lee; G Dube; M R Pereira
Journal:  Transpl Infect Dis       Date:  2015-11-05       Impact factor: 2.228

5.  Is early removal of prophylactic ureteric stents beneficial in live donor renal transplantation?

Authors:  K N Indu; G Lakshminarayana; M Anil; R Rajesh; K George; K Ginil; M Georgy; B Nair; S Sudhindran; T Appu; V N Unni; K V Sanjeevan
Journal:  Indian J Nephrol       Date:  2012-07

6.  Urinary ATP and visualization of intracellular bacteria: a superior diagnostic marker for recurrent UTI in renal transplant recipients?

Authors:  Stephen P Kelley; Holly R Courtneidge; Rebecca E Birch; Alberto Contreras-Sanz; Mark C Kelly; Jerome Durodie; Claire M Peppiatt-Wildman; Christopher K Farmer; Michael P Delaney; James Malone-Lee; Mark A Harber; Scott S Wildman
Journal:  Springerplus       Date:  2014-04-23

7.  Risk and outcome of pyelonephritis among renal transplant recipients.

Authors:  Mette Elneff Graversen; Lars Skov Dalgaard; Søren Jensen-Fangel; Bente Jespersen; Lars Østergaard; Ole Schmeltz Søgaard
Journal:  BMC Infect Dis       Date:  2016-06-10       Impact factor: 3.090

  7 in total

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