M J Courtney1, D Cabraal. 1. Department of Otolaryngology-Head and Neck Surgery, Wellington Hospital, Private Bag 7902, Wellington South, New Zealand. mark.richelle@paradise.net.nz
Abstract
OBJECTIVE: To compare the analgesic efficacy of oral tramadol hydrochloride and oral diclofenac sodium for posttonsillectomy pain management. DESIGN: Single-blind (surgeon and research team members), prospective, randomized, controlled clinical trial. PATIENTS AND METHODS: Sixty-four patients 11 years and older undergoing bipolar electrocautery tonsillectomy were randomized to either the oral tramadol or the oral diclofenac postoperative pain group. Patients recorded pain levels twice daily for 14 days using a visual analogue scale. RESULTS:Pain scores for the 14 days were not significantly different between the oral tramadol and oral diclofenac groups. There were no significant differences in the incidence of postoperative hemorrhage and hospital readmission for uncontrolled pain. CONCLUSION:Oral tramadol can deliver the same analgesic efficacy as oral diclofenac for posttonsillectomy pain relief, which might be beneficial for avoiding the adverse effects of nonsteroidal anti-inflammatory drug therapy.
RCT Entities:
OBJECTIVE: To compare the analgesic efficacy of oral tramadol hydrochloride and oral diclofenac sodium for posttonsillectomy pain management. DESIGN: Single-blind (surgeon and research team members), prospective, randomized, controlled clinical trial. PATIENTS AND METHODS: Sixty-four patients 11 years and older undergoing bipolar electrocautery tonsillectomy were randomized to either the oral tramadol or the oral diclofenacpostoperative pain group. Patients recorded pain levels twice daily for 14 days using a visual analogue scale. RESULTS:Pain scores for the 14 days were not significantly different between the oral tramadol and oral diclofenac groups. There were no significant differences in the incidence of postoperative hemorrhage and hospital readmission for uncontrolled pain. CONCLUSION: Oral tramadol can deliver the same analgesic efficacy as oral diclofenac for posttonsillectomy pain relief, which might be beneficial for avoiding the adverse effects of nonsteroidal anti-inflammatory drug therapy.
Authors: I Tagarro; J Herrera; C Barutell; M C Díez; M Marín; D Samper; C Busquet; M J Rodríguez Journal: Clin Drug Investig Date: 2005 Impact factor: 2.859
Authors: Alexander Schnabel; Sylvia U Reichl; Christine Meyer-Frießem; Peter K Zahn; Esther Pogatzki-Zahn Journal: Cochrane Database Syst Rev Date: 2015-03-18