Literature DB >> 11295813

Quality of life and oral function in patients treated with radiation therapy for head and neck cancer.

J B Epstein1, M Robertson, S Emerton, N Phillips, P Stevenson-Moore.   

Abstract

BACKGROUND: Multiple oral complaints develop during radiation therapy for head and neck cancer, and quality of life is affected after treatment. The purpose of this investigation was to assess the quality of life, oral function, and oral symptoms in a cohort of patients during and after radiation therapy.
METHODS: A general quality of life survey (the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30), with an added oral symptom and function scale was administered to a consecutive series of patients who received radiation therapy for head and neck malignant disease. Patients completed surveys at the beginning of radiation therapy, immediately after, and 6 months after treatment. RESULTS AND DISCUSSION: The questionnaire used in this study provides increased information regarding the oral and dental function that is frequently affected by radiation therapy. Results of this study indicate the need to determine oral dysfunction after head and neck cancer therapy, so that the most predictable cure or best palliation of the malignancy with the least impact on oral function and quality of life is chosen. Oral complications during and after radiation therapy for head and neck cancer are common and affect quality of life. Oral QOL does not return to pretreatment levels by 6 months after radiation therapy. This study supports the use of a general function scale such as the EORTC questionnaire with the addition of disease/site-specific scales to provide data on outcomes of therapy and on the complications associated with therapy. The EORTC QLQ 30 questionnaire with the oral assessment addendum provides a measure of the quality of life and oral function in head and neck cancer patients and may provide useful outcome measures for assessment of oral care prevention and management strategies in these patient populations. The results show that the questionnaire is responsive to change throughout the course of radiation therapy for head and neck cancer. Copyright 2001 John Wiley & Sons, Inc.

Entities:  

Mesh:

Year:  2001        PMID: 11295813     DOI: 10.1002/hed.1049

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  64 in total

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2.  The impact of taste and smell alterations on quality of life in head and neck cancer patients.

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5.  A prospective evaluation of short-term health-related quality of life in patients undergoing anterior skull base surgery.

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8.  Survivorship Challenges and Information Needs after Radiotherapy for Oral Cancer.

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9.  Recombinant AAV9-TLK1B administration ameliorates fractionated radiation-induced xerostomia.

Authors:  Prakash Srinivasan Timiri Shanmugam; Robert D Dayton; Senthilnathan Palaniyandi; Fleurette Abreo; Gloria Caldito; Ronald L Klein; Gulshan Sunavala-Dossabhoy
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10.  Neuropathic and nociceptive pain in head and neck cancer patients receiving radiation therapy.

Authors:  Joel B Epstein; Diana J Wilkie; Dena J Fischer; Young-Ok Kim; Dana Villines
Journal:  Head Neck Oncol       Date:  2009-07-14
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