Literature DB >> 11294822

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions.

G Pearson1, F Robinson, T Beers Gibson, B E Xu, M Karandikar, K Berman, M H Cobb.   

Abstract

Mitogen-activated protein (MAP) kinases comprise a family of ubiquitous proline-directed, protein-serine/threonine kinases, which participate in signal transduction pathways that control intracellular events including acute responses to hormones and major developmental changes in organisms. MAP kinases lie in protein kinase cascades. This review discusses the regulation and functions of mammalian MAP kinases. Nonenzymatic mechanisms that impact MAP kinase functions and findings from gene disruption studies are highlighted. Particular emphasis is on ERK1/2.

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Year:  2001        PMID: 11294822     DOI: 10.1210/edrv.22.2.0428

Source DB:  PubMed          Journal:  Endocr Rev        ISSN: 0163-769X            Impact factor:   19.871


  1265 in total

1.  ERK2 enters the nucleus by a carrier-independent mechanism.

Authors:  Angelique W Whitehurst; Julie L Wilsbacher; Youngjai You; Kate Luby-Phelps; Mary Shannon Moore; Melanie H Cobb
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-28       Impact factor: 11.205

Review 2.  Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets.

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Journal:  Gut       Date:  2003-01       Impact factor: 23.059

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Review 4.  The RNA polymerase II CTD "orphan" residues: Emerging insights into the functions of Tyr-1, Thr-4, and Ser-7.

Authors:  Nathan M Yurko; James L Manley
Journal:  Transcription       Date:  2017-10-04

Review 5.  GnRH signaling, the gonadotrope and endocrine control of fertility.

Authors:  Stuart P Bliss; Amy M Navratil; Jianjun Xie; Mark S Roberson
Journal:  Front Neuroendocrinol       Date:  2010-05-06       Impact factor: 8.606

6.  Sustained MAPK/ERK Activation in Adult Schwann Cells Impairs Nerve Repair.

Authors:  Ilaria Cervellini; Jorge Galino; Ning Zhu; Shannen Allen; Carmen Birchmeier; David L Bennett
Journal:  J Neurosci       Date:  2017-12-07       Impact factor: 6.167

7.  An immune-stimulating proteoglycan from the medicinal mushroom Huaier up-regulates NF-κB and MAPK signaling via Toll-like receptor 4.

Authors:  Ailin Yang; Haitao Fan; Yanan Zhao; Xiaonan Chen; Zhixiang Zhu; Xiaojun Zha; Yunfang Zhao; Xingyun Chai; Jun Li; Pengfei Tu; Zhongdong Hu
Journal:  J Biol Chem       Date:  2019-01-02       Impact factor: 5.157

8.  Rit-mediated stress resistance involves a p38-mitogen- and stress-activated protein kinase 1 (MSK1)-dependent cAMP response element-binding protein (CREB) activation cascade.

Authors:  Geng-Xian Shi; Weikang Cai; Douglas A Andres
Journal:  J Biol Chem       Date:  2012-10-04       Impact factor: 5.157

9.  Cancer as robust intrinsic state of endogenous molecular-cellular network shaped by evolution.

Authors:  Ping Ao; David Galas; Leroy Hood; Xiaomei Zhu
Journal:  Med Hypotheses       Date:  2007-09-04       Impact factor: 1.538

10.  GRASP-1 is a neuronal scaffold protein for the JNK signaling pathway.

Authors:  Bing Ye; Wei-ping Yu; Gareth M Thomas; Richard L Huganir
Journal:  FEBS Lett       Date:  2007-08-14       Impact factor: 4.124

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