Literature DB >> 11294794

Clustering of highly homologous sequences to reduce the size of large protein databases.

W Li1, L Jaroszewski, A Godzik.   

Abstract

We present a fast and flexible program for clustering large protein databases at different sequence identity levels. It takes less than 2 h for the all-against-all sequence comparison and clustering of the non-redundant protein database of over 560,000 sequences on a high-end PC. The output database, including only the representative sequences, can be used for more efficient and sensitive database searches.

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Year:  2001        PMID： 11294794     DOI： 10.1093/bioinformatics/17.3.282

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


  312 in total

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4.  UniqueProt: Creating representative protein sequence sets.

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Journal:  Genetica       Date:  2012-04-29       Impact factor: 1.082

9.  Spatial variability in airborne bacterial communities across land-use types and their relationship to the bacterial communities of potential source environments.

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10.  Internal duplications in α-helical membrane protein topologies are common but the nonduplicated forms are rare.

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Journal:  Protein Sci       Date:  2010-12       Impact factor: 6.725
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