| Literature DB >> 1129143 |
B E Kessler-Liebscher, W L Staudenbauer, P H Hofschneider.
Abstract
Pulse-labeled replicative intermediates in M 13 single stranded DNA synthesis can be separated by dye-buoyant density centrifugation into two major fractions: Supercoiled molecules (RI I) containing viral strands of more than one genome length, and "relaxed" molecules (RI II) with labeled DNA chains shorter than unit length. It is postulated that RI II molecules might be formed in vivo by site-specific nicking of RF I molecules.Entities:
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Year: 1975 PMID: 1129143 PMCID: PMC342817 DOI: 10.1093/nar/2.1.131
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971