Literature DB >> 11287874

Impact of antibiotic prophylaxis on wound infection after cesarean section in a situation of expected higher risk.

M W Mah1, A M Pyper, G A Oni, Z A Memish.   

Abstract

BACKGROUND: To measure rates of incisional surgical site infection (ISSI) after cesarean section (CS) and to assess risks for infection.
METHODS: Prospective surveillance for ISSI at a 540-bed hospital in Saudi Arabia by using Centers for Disease Control and Prevention definitions for infection and the National Nosocomial Infections Surveillance (NNIS) system risk index.
RESULTS: Seven hundred thirty-five CSs were studied from September 1998 to July 1999; 72% were emergency procedures, despite a 95% rate of antenatal care. The overall ISSI rate was 2.8% (95% confidence interval [CI], 1.7%-4.3%). The rate for NNIS risk category 0 was 2.4% (95% CI, 1.3%-4.2%; n = 536) and for category 1 was 4.1% (95% CI, 1.8%-8.6%; n = 170). In the multivariate analysis, the only independent risks for ISSI were duration of surgery (OR = 1.01; 95% CI, 1.00-1.03; P =.02) and no antibiotic prophylaxis (OR = 3.09; 95% CI, 1.10-9.11; P =.04). Antibiotic prophylaxis was inconsistently administered among both emergency and elective CS. Infection control procedures were inadequate in the obstetric suite operating room.
CONCLUSIONS: Despite deficient infection control practices in the setting described, ISSI rates after CS were judged "acceptable" compared with NNIS benchmark rates. This was attributed to prescribing antibiotic prophylaxis for patients at low risk as well as high risk of infection.

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Year:  2001        PMID: 11287874     DOI: 10.1067/mic.2001.111372

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN: 0196-6553            Impact factor:   2.918


  5 in total

1.  A study of post-caesarean section wound infections in a regional referral hospital, oman.

Authors:  Hansa Dhar; Ibrahim Al-Busaidi; Bhawna Rathi; Eman A Nimre; Vibha Sachdeva; Ilham Hamdi
Journal:  Sultan Qaboos Univ Med J       Date:  2014-04-07

Review 2.  Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section.

Authors:  Fiona M Smaill; Rosalie M Grivell
Journal:  Cochrane Database Syst Rev       Date:  2014-10-28

3.  A randomized controlled trial comparing two different antibiotic regimens for prophylaxis at cesarean section.

Authors:  Gourisankar Kamilya; Subrata Lall Seal; Joydev Mukherji; Himangsu Roy; Subir Kumar Bhattacharyya; Avijit Hazra
Journal:  J Obstet Gynaecol India       Date:  2012-04-20

Review 4.  Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section.

Authors:  Fiona M Smaill; Gillian Ml Gyte
Journal:  Cochrane Database Syst Rev       Date:  2010-01-20

5.  Infectious morbidity after cesarean delivery: 10 strategies to reduce risk.

Authors:  Kelley Conroy; Angela F Koenig; Yan-Hong Yu; Amy Courtney; Hee Joong Lee; Errol R Norwitz
Journal:  Rev Obstet Gynecol       Date:  2012
  5 in total

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