Literature DB >> 11287116

Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2).

K Yamamoto1, Y Fujiyama, A Andoh, T Bamba, H Okabe.   

Abstract

The human major histocompatibility complex class I chain-related A gene (MICA) and the MICB gene are newly identified members of the major histocompatibility complex class I chain-related gene family. We demonstrate here that oxidative stress, induced by H(2)O(2), promoted MICA (2.2-fold) and MICB (3.8-fold) gene expression using the human colon carcinoma cell line (CaCo-2) and semi-quantitative RT-PCR.

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Year:  2001        PMID： 11287116     DOI： 10.1016/s0304-4165(01)00099-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  34 in total

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10.  Combined effect of hydrogen peroxide induced oxidative stress and IL-1 alpha on IL-8 production in CaCo-2 cells (a human colon carcinoma cell line) and normal intestinal epithelial cells.

Authors:  Kazuo Yamamoto; Ryoji Kushima; Osamu Kisaki; Yoshihide Fujiyama; Hidetoshi Okabe
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