| Literature DB >> 11286708 |
Abstract
The activity of the chemokine RANTES is not restricted merely to chemotaxis. It is a powerful leukocyte activator, a feature potentially relevant in a range of inflammatory disorders. RANTES has attracted attention because it can potently suppress and, in some circumstances, enhance HIV replication. These characteristics are critically dependent on its ability to self-aggregate and bind to glycosaminoglycans.Entities:
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Year: 2001 PMID: 11286708 DOI: 10.1016/s1471-4906(00)01812-3
Source DB: PubMed Journal: Trends Immunol ISSN: 1471-4906 Impact factor: 16.687