| Literature DB >> 11286689 |
M Los1, C Stroh, R U Jänicke, I H Engels, K Schulze-Osthoff.
Abstract
Proteases of the caspase family constitute the central executioners of apoptosis. Several recent observations suggest that caspases and apoptosis-regulatory molecules exert important functions beyond that of cell death, including the control of T-cell proliferation and cell-cycle progression. Here, Los and colleagues propose a model that directly connects cell suicide mechanisms to the regulation of cell-cycle progression.Mesh:
Substances:
Year: 2001 PMID: 11286689 DOI: 10.1016/s1471-4906(00)01814-7
Source DB: PubMed Journal: Trends Immunol ISSN: 1471-4906 Impact factor: 16.687