Literature DB >> 11286647

Atherogenesis and the arginine hypothesis.

J P Cooke1, R K Oka.   

Abstract

In patients who have elevated levels of plasma ADMA, a relative deficiency of L-arginine has been found to contribute to the pathophysiology of athersclerosis, causing vasoconstriction, and accelerating atherogenesis. This finding--that there is a relative deficiency of L-arginine in atherosclerotic disease--is a breakthrough that will open new avenues of therapy.

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Year:  2001        PMID： 11286647     DOI： 10.1007/s11883-001-0068-x

Source DB:  PubMed          Journal:  Curr Atheroscler Rep        ISSN： 1523-3804            Impact factor:   5.113


  87 in total

1.  Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction.

Authors:  J A Suwaidi; S Hamasaki; S T Higano; R A Nishimura; D R Holmes; A Lerman
Journal:  Circulation       Date:  2000-03-07       Impact factor: 29.690

2.  N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor.

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Journal:  Circ Res       Date:  1989-09       Impact factor: 17.367

3.  Purification and molecular identification of two protein methylases I from calf brain. Myelin basic protein- and histone-specific enzyme.

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Journal:  J Biol Chem       Date:  1988-12-15       Impact factor: 5.157

4.  Modulation of expression of endothelial nitric oxide synthase by nordihydroguaiaretic acid, a phenolic antioxidant in cultured endothelial cells.

Authors:  S Ramasamy; G R Drummond; J Ahn; M Storek; J Pohl; S Parthasarathy; D G Harrison
Journal:  Mol Pharmacol       Date:  1999-07       Impact factor: 4.436

5.  Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor.

Authors:  G M Rubanyi; P M Vanhoutte
Journal:  Am J Physiol       Date:  1986-05

6.  Treatment with L-arginine is likely to stimulate generation of nitric oxide in patients with peripheral arterial obstructive disease.

Authors:  R J Gryglewski; L Grodzińska; E Kostka-Trabka; R Korbut; K Bieroón; A Goszcz; M Sławiński
Journal:  Wien Klin Wochenschr       Date:  1996       Impact factor: 1.704

7.  Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase.

Authors:  R J MacAllister; H Parry; M Kimoto; T Ogawa; R J Russell; H Hodson; G S Whitley; P Vallance
Journal:  Br J Pharmacol       Date:  1996-12       Impact factor: 8.739

8.  Isolation and identification of N-G,N-G- and N-G,N'-G-dimethyl-arginine, N-epsilon-mono-, di-, and trimethyllysine, and glucosylgalactosyl- and galactosyl-delta-hydroxylysine from human urine.

Authors:  Y Kakimoto; S Akazawa
Journal:  J Biol Chem       Date:  1970-11-10       Impact factor: 5.157

9.  Studies on the catabolism of Ng-methylarginine, Ng, Ng-dimethylarginine and Ng, Ng-dimethylarginine in the rabbit.

Authors:  J R McDermott
Journal:  Biochem J       Date:  1976-01-15       Impact factor: 3.857

10.  Increased endogenous nitric oxide synthase inhibitor in patients with congestive heart failure.

Authors:  M Usui; H Matsuoka; H Miyazaki; S Ueda; S Okuda; T Imaizumi
Journal:  Life Sci       Date:  1998       Impact factor: 5.037
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  8 in total

Review 1.  Effect of diet on vascular reactivity: an emerging marker for vascular risk.

Authors:  S G West
Journal:  Curr Atheroscler Rep       Date:  2001-11       Impact factor: 5.113

Review 2.  Dietary factors in atherogenesis.

Authors:  Margaret-Mary G Wilson; David R Thomas
Journal:  Curr Atheroscler Rep       Date:  2003-07       Impact factor: 5.113

3.  Physical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice.

Authors:  Claudio Napoli; Sharon Williams-Ignarro; Filomena de Nigris; Lilach O Lerman; Francesco P D'Armiento; Ettore Crimi; Russell E Byrns; Amelia Casamassimi; Alessandro Lanza; Fernando Gombos; Vincenzo Sica; Louis J Ignarro
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-26       Impact factor: 11.205

Review 4.  Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis.

Authors:  Louis J Ignarro; Claudio Napoli
Journal:  Curr Diab Rep       Date:  2005-02       Impact factor: 4.810

5.  Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.

Authors:  Claudio Napoli; Sharon Williams-Ignarro; Filomena de Nigris; Gaetano de Rosa; Lilach O Lerman; Bartolomeo Farzati; Angelo Matarazzo; Giacomo Sica; Chiara Botti; Andrea Fiore; Russell E Byrns; Daigo Sumi; Vincenzo Sica; Louis J Ignarro
Journal:  Proc Natl Acad Sci U S A       Date:  2005-11-14       Impact factor: 11.205

Review 6.  Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis.

Authors:  Louis J Ignarro; Claudio Napoli
Journal:  Curr Atheroscler Rep       Date:  2004-07       Impact factor: 5.113

7.  Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress.

Authors:  Filomena de Nigris; Lilach O Lerman; Sharon Williams Ignarro; Giacomo Sica; Amir Lerman; Wulf Palinski; Louis J Ignarro; Claudio Napoli
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-13       Impact factor: 11.205

8.  Is type 2 diabetes mellitus a vascular disease (atheroscleropathy) with hyperglycemia a late manifestation? The role of NOS, NO, and redox stress.

Authors:  Melvin R Hayden; Suresh C Tyagi
Journal:  Cardiovasc Diabetol       Date:  2003-02-12       Impact factor: 9.951
  8 in total

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