Literature DB >> 11286464

Randomized trial of adjuvant chemotherapy versus control after curative resection for gastric cancer: 5-year follow-up.

B Neri1, G Cini, F Andreoli, B Boffi, D Francesconi, R Mazzanti, F Medi, A Mercatelli, S Romano, L Siliani, R Tarquini, R Moretti.   

Abstract

Adjuvant chemotherapy of gastric cancer after curative resection is still subject to discussion. In this study 137 patients with gastric adenocarcinoma, all with positive nodes, were randomized after curative resection so that 69 received epidoxorubicin (EPI), leucovorin (LV) and 5-fluorouracil (5-FU) on days 1-3 every 3 weeks for 7 months, whereas the remaining 68 did not. After a follow-up period of 5 years, 21 of the 69 treated patients (30%) and nine controls (13%) were still alive; median survival time was 18 months for the controls and 31 months for the patients treated with adjuvant chemotherapy (P< 0.01). Copyright 2001 Cancer Research Campaign.

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Year:  2001        PMID： 11286464      PMCID： PMC2363834          DOI： 10.1054/bjoc.2000.1472

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  23 in total

1.  Neoadjuvant S-1 and cisplatin for gastric carcinoma: there will be more to come.

Authors:  Yasuhiro Kodera
Journal:  Gastric Cancer       Date:  2006       Impact factor: 7.370

2.  Predicting individual survival after gastric cancer resection: validation of a U.S.-derived nomogram at a single high-volume center in Europe.

Authors:  Alexander R Novotny; Christoph Schuhmacher; Raymonde Busch; Michael W Kattan; Murray F Brennan; Jörg Rüdiger Siewert
Journal:  Ann Surg       Date:  2006-01       Impact factor: 12.969

3.  Comparison of two different adjuvant treatment modalities for pN3 gastric cancer patients after D2 lymph node dissection: can we avoid radiotherapy in a subgroup of patients?

Authors:  Leyla Kilic; Cetin Ordu; Meltem Ekenel; Ibrahim Yildiz; Serkan Keskin; Fatma Sen; Zeynep Gural; Oktar Asoglu; Ahmet Kizir; Faruk Aykan
Journal:  Med Oncol       Date:  2013-07-23       Impact factor: 3.064

Review 4.  Surgery and adjuvant chemotherapy.

Authors:  Mitsuru Sasako
Journal:  Int J Clin Oncol       Date:  2008-06-14       Impact factor: 3.402

5.  Chemotherapy for operable gastric cancer: current perspectives.

Authors:  Vikram K Jain; David Cunningham; Sheela Rao
Journal:  Indian J Surg Oncol       Date:  2012-03-01

6.  In vitro chemosensitivity test to predict chemosensitivity for paclitaxel, using human gastric carcinoma tissues.

Authors:  Yasuhiro Kodera; Seiji Ito; Michitaka Fujiwara; Yoshinari Mochizuki; Norifumi Ohashi; Yuichi Ito; Goro Nakayama; Masahiko Koike; Yoshitaka Yamamura; Akimasa Nakao
Journal:  Int J Clin Oncol       Date:  2006-12-25       Impact factor: 3.402

Review 7.  Treatment of gastric cancer.

Authors:  Michele Orditura; Gennaro Galizia; Vincenzo Sforza; Valentina Gambardella; Alessio Fabozzi; Maria Maddalena Laterza; Francesca Andreozzi; Jole Ventriglia; Beatrice Savastano; Andrea Mabilia; Eva Lieto; Fortunato Ciardiello; Ferdinando De Vita
Journal:  World J Gastroenterol       Date:  2014-02-21       Impact factor: 5.742

Review 8.  Current adjuvant treatment modalities for gastric cancer: From history to the future.

Authors:  Leyla Kilic; Cetin Ordu; Ibrahim Yildiz; Fatma Sen; Serkan Keskin; Rumeysa Ciftci; Kezban Nur Pilanci
Journal:  World J Gastrointest Oncol       Date:  2016-05-15

Review 9.  Stomach cancer.

Authors:  Charles Bailey
Journal:  BMJ Clin Evid       Date:  2008-09-03

Review 10.  Chemotherapy for patients with gastric cancer after complete resection: a network meta-analysis.

Authors:  Ya-Wu Zhang; Yu-Long Zhang; Hui Pan; Feng-Xian Wei; You-Cheng Zhang; Yuan Shao; Wei Han; Hai-Peng Liu; Zhe-Yuan Wang; Sun-Hu Yang
Journal:  World J Gastroenterol       Date:  2014-01-14       Impact factor: 5.742
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