| Literature DB >> 11284510 |
Abstract
A short and practical route to 3-O-benzoyl azidosphingosine from D-xylose is described. The synthesis avoids the use of expensive and hazardous chemicals (i.e. mercury salts), and it is reproducible up to at least a 20 g scale. Furthermore, the synthesis proceeds to 3-O-benzoyl azidosphingosine with a minimum of protection group manipulation, by exploiting a regioselective protection of the primary HO-1 with thexyldimethylsilyl chloride.Entities:
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Year: 2001 PMID： 11284510 DOI： 10.1016/s0008-6215(00)00323-2
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104