Literature DB >> 11284499

An improved synthesis of the saponin, polyphyllin D.

B Li1, B Yu, Y Hui, M Li, X Han, K P Fung.   

Abstract

Polyphyllin D, namely diosgenyl alpha-L-rhamnopyranosyl-(1 --> 2)- [(alpha-L-arabinofuranosyl)-(1 --> 4)]-[beta-D-glucopyranoside, was synthesized from diosgenyl-beta-D-glucopyranoside in four steps and in 30% overall yield, taking advantage of regioselective pivaloylation and alpha-L-rhamnopyranosylation reactions.

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Year:  2001        PMID： 11284499     DOI： 10.1016/s0008-6215(01)00014-3

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  6 in total

1.  Polyphyllin D, a steroidal saponin in Paris polyphylla, induces apoptosis and necroptosis cell death of neuroblastoma cells.

Authors:  Shunsuke Watanabe; Tatuya Suzuki; Fujio Hara; Toshihiro Yasui; Naoko Uga; Atuki Naoe
Journal:  Pediatr Surg Int       Date:  2017-03-04       Impact factor: 1.827

2.  Introducing N-glycans into natural products through a chemoenzymatic approach.

Authors:  Wei Huang; Hirofumi Ochiai; Xinyu Zhang; Lai-Xi Wang
Journal:  Carbohydr Res       Date:  2008-09-09       Impact factor: 2.104

3.  Paris chinensis dioscin induces G2/M cell cycle arrest and apoptosis in human gastric cancer SGC-7901 cells.

Authors:  Lin-Lin Gao; Fu-Rong Li; Peng Jiao; Ming-Feng Yang; Xiao-Jun Zhou; Yan-Hong Si; Wen-Jian Jiang; Ting-Ting Zheng
Journal:  World J Gastroenterol       Date:  2011-10-21       Impact factor: 5.742

4.  Paris saponin I induces G₂/M cell cycle arrest and apoptosis in human gastric carcinoma SGC7901 cells.

Authors:  Meifang Xiao; Xiahong Dai; Xinchun He; Rongrong Zhou; Baoxin Zhang; Guansheng Hu; Zebing Huang; Xuegong Fan
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2011-12-16

5.  Antitumor effect of polyphyllin D on liver metastases of neuroblastoma.

Authors:  Yasuhiro Kondo; Shunsuke Watanabe; Atsuki Naoe; Toshiyuki Takeuchi; Atsuko Niimi; Motoshi Suzuki; Naoya Asai; Seiji Okada; Tomonori Tsuchiya; Mika Murayama; Toshihiro Yasui; Mikihiro Inoue; Tatsuya Suzuki
Journal:  Pediatr Surg Int       Date:  2022-06-14       Impact factor: 1.827

6.  N-Alkyl derivatives of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside; synthesis and antimicrobial activity.

Authors:  Agata Walczewska; Daria Grzywacz; Dorota Bednarczyk; Małgorzata Dawgul; Andrzej Nowacki; Wojciech Kamysz; Beata Liberek; Henryk Myszka
Journal:  Beilstein J Org Chem       Date:  2015-05-22       Impact factor: 2.883
  6 in total

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