Literature DB >> 11284000

Improved selectivity of double quantum coherence filtering for the detection of glutathione in the human brain in vivo.

A H Trabesinger1, P Boesiger.   

Abstract

An improved double quantum coherence (DQC) filter for the selective in vivo detection of glutathione (GSH) in the human brain at 1.5 Tesla is presented. The goal was to minimize contamination of the DQC-filtered GSH signal at 2.9 ppm with contributions arising from GABA. The modification consists of tailoring the frequency response of the read pulse, which converts DQC into anti-phase single quantum coherence in such a way that the GABA beta and gamma resonances at 3.0 and 1.9 ppm, respectively, remain unaffected. An implementation incorporating a Dante pulse train is used for in vitro tests as well as for in vivo applications. Magn Reson Med 45:708-710, 2001. Copyright 2001 Wiley-Liss, Inc.

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Year:  2001        PMID： 11284000     DOI： 10.1002/mrm.1094

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN： 0740-3194            Impact factor:   4.668


  12 in total

1.  Lower levels of glutathione in the brains of secondary progressive multiple sclerosis patients measured by 1H magnetic resonance chemical shift imaging at 3 T.

Authors:  I-Y Choi; S-P Lee; D R Denney; S G Lynch
Journal:  Mult Scler       Date:  2010-10-04       Impact factor: 6.312

2.  Doubly selective multiple quantum chemical shift imaging and T(1) relaxation time measurement of glutathione (GSH) in the human brain in vivo.

Authors:  In-Young Choi; Phil Lee
Journal:  NMR Biomed       Date:  2012-06-22       Impact factor: 4.044

3.  Multi-center reproducibility of neurochemical profiles in the human brain at 7 T.

Authors:  B L van de Bank; U E Emir; V O Boer; J J A van Asten; M C Maas; J P Wijnen; H E Kan; G Oz; D W J Klomp; T W J Scheenen
Journal:  NMR Biomed       Date:  2015-01-08       Impact factor: 4.044

4.  Pilot results of in vivo brain glutathione measurements in stroke patients.

Authors:  Li An; Krishna A Dani; Jun Shen; Steven Warach
Journal:  J Cereb Blood Flow Metab       Date:  2012-09-26       Impact factor: 6.200

5.  Contribution of NMR spectroscopy to the differential diagnosis of a recurrent cranial mass 7 years after irradiation for a pediatric ependymoma.

Authors:  Isabelle Rutten; Daniel Raket; Nadine Francotte; Pierre Philippet; Shih-Li Chao; Marc Lemort
Journal:  Childs Nerv Syst       Date:  2006-05-18       Impact factor: 1.475

6.  Spurious signals in DQF spectroscopy: two-shot stimulated echoes.

Authors:  Jacqueline Pictet; J J van der Klink; R Meuli
Journal:  MAGMA       Date:  2004-10-26       Impact factor: 2.310

7.  Memory recall involves a transient break in excitatory-inhibitory balance.

Authors:  Renée S Koolschijn; Anna Shpektor; William T Clarke; I Betina Ip; David Dupret; Uzay E Emir; Helen C Barron
Journal:  Elife       Date:  2021-10-08       Impact factor: 8.140

8.  Measurement of glutathione in normal volunteers and stroke patients at 3T using J-difference spectroscopy with minimized subtraction errors.

Authors:  Li An; Yan Zhang; David M Thomasson; Lawrence L Latour; Eva H Baker; Jun Shen; Steven Warach
Journal:  J Magn Reson Imaging       Date:  2009-08       Impact factor: 4.813

9.  Measurement of glutathione in human brain at 3T using an improved double quantum filter in vivo.

Authors:  Changho Choi; Chenguang Zhao; Ivan Dimitrov; Deborah Douglas; Nicholas J Coupland; Sanjay Kalra; Halima Hawesa; Jeannie Davis
Journal:  J Magn Reson       Date:  2009-02-13       Impact factor: 2.229

Review 10.  Imaging glutamate in schizophrenia: review of findings and implications for drug discovery.

Authors:  E M P Poels; L S Kegeles; J T Kantrowitz; M Slifstein; D C Javitt; J A Lieberman; A Abi-Dargham; R R Girgis
Journal:  Mol Psychiatry       Date:  2013-10-29       Impact factor: 15.992
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