Literature DB >> 11283383

Community use of intravenous tissue plasminogen activator for acute stroke: results of the brain matters stroke management survey.

I L Katzan1, C A Sila, A J Furlan.   

Abstract

BACKGROUND AND
PURPOSE: Little is known of neurologists' viewpoints regarding intravenous tPA use or institutional readiness to evaluate potential thrombolytic candidates.
METHODS: Surveys were distributed at the Brain Matters Stroke Management Workshops held in 16 cities in the United States.
RESULTS: Intravenous tPA was administered by 46.9% of responding neurologists. Almost 30% (29.9%) of surveyed neurologists were "very convinced" of its efficacy, whereas 61.6% were "very concerned" about the risk of intracranial hemorrhage. Only half of the respondents believed their institutions could meet all NINDS-recommended stroke-evaluation time targets.
CONCLUSIONS: Neurologists' enthusiasm for the efficacy of intravenous tPA is tempered by their concern about intracranial hemorrhage. Institutional readiness for evaluating acute stroke patients is not optimized.

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Year:  2001        PMID: 11283383     DOI: 10.1161/01.str.32.4.861

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  8 in total

Review 1.  Thrombolysis in acute ischaemic stroke: a guide to patient selection.

Authors:  Richard I Lindley
Journal:  CNS Drugs       Date:  2005       Impact factor: 5.749

2.  Intravenous thrombolysis in acute ischaemic stroke: from trial exclusion criteria to clinical contraindications. An international Delphi study.

Authors:  Maaike Dirks; Louis W Niessen; Peter J Koudstaal; Cees L Franke; Robert J van Oostenbrugge; Diederik W J Dippel
Journal:  J Neurol Neurosurg Psychiatry       Date:  2007-03-01       Impact factor: 10.154

Review 3.  Enhancing community delivery of tissue plasminogen activator in stroke through community-academic collaborative clinical knowledge translation.

Authors:  Phillip A Scott
Journal:  Emerg Med Clin North Am       Date:  2009-02       Impact factor: 2.264

Review 4.  Stroke, dementia, and drug delivery.

Authors:  G A Ford; C A Bryant; A A Mangoni; S H D Jackson
Journal:  Br J Clin Pharmacol       Date:  2004-01       Impact factor: 4.335

5.  Medico-legal aspects of using tissue plasminogen activator in acute ischemic stroke.

Authors:  Nhu T Bruce; William P Neil; Justin A Zivin
Journal:  Curr Treat Options Cardiovasc Med       Date:  2011-06

6.  Chinese neurologists' perspective on intravenous thrombolysis for acute ischemic stroke.

Authors:  Meng-Die Wang; Xiao-Xv Yin; Ting-Ting Yang; Yong Wang; Yi-Yi Zhu; Yan-Feng Zhou; Zu-Xun Lu; Bo Hu
Journal:  Brain Behav       Date:  2017-12-07       Impact factor: 2.708

Review 7.  Medicolegal considerations with intravenous tissue plasminogen activator in stroke: a systematic review.

Authors:  Archit Bhatt; Adnan Safdar; Dhara Chaudhari; Diane Clark; Amber Pollak; Arshad Majid; Mounzer Kassab
Journal:  Stroke Res Treat       Date:  2013-09-04

8.  Determining intravenous rt-PA eligibility in the Emergency Department.

Authors:  Amy C Mecozzi; Devin L Brown; Lynda D Lisabeth; William G Barsan; Robert Silbergleit; Susan L Hickenbottom; Phillip A Scott; Lewis B Morgenstern
Journal:  Neurocrit Care       Date:  2007       Impact factor: 3.532

  8 in total

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