Literature DB >> 11283359

Ecology. The advantages of togetherness.

E Cox1, J Bonner.   

Abstract

What would be the advantage of unicellular organisms becoming multicellular? For organisms that feed on organic food (heterotrophs), the most efficient way to produce energy is to metabolize the food by aerobic respiration, but the fastest way is to metabolize it by fermentation. In their Perspective, Cox and Bonner discuss a mathematical model (Pfeiffer et al.), which shows that when these two kinds of organisms (respirators and fermenters) compete for a limited food source, the respirators manage best when they are grouped in clusters rather than remaining as separate cells. In this way, multicellularity could have originated.

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Year:  2001        PMID: 11283359     DOI: 10.1126/science.1060456

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

Review 1.  Cancer metabolism: a therapeutic perspective.

Authors:  Ubaldo E Martinez-Outschoorn; Maria Peiris-Pagés; Richard G Pestell; Federica Sotgia; Michael P Lisanti
Journal:  Nat Rev Clin Oncol       Date:  2016-05-04       Impact factor: 66.675

2.  Editorial: Cancer Ecosystems.

Authors:  Ubaldo E Martinez-Outschoorn; Mireia Bartrons; Ramon Bartrons
Journal:  Front Oncol       Date:  2019-08-20       Impact factor: 6.244

Review 3.  Mitochondrial Flexibility of Breast Cancers: A Growth Advantage and a Therapeutic Opportunity.

Authors:  Angelica Avagliano; Maria Rosaria Ruocco; Federica Aliotta; Immacolata Belviso; Antonello Accurso; Stefania Masone; Stefania Montagnani; Alessandro Arcucci
Journal:  Cells       Date:  2019-04-30       Impact factor: 6.600

  3 in total

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