Literature DB >> 11282342

Combinatorial biosynthesis of polyketides and nonribosomal peptides.

J Staunton1, B Wilkinson.   

Abstract

The engineering of polyketide biosynthesis has begun to provide robust targeted libraries for screening against pharmaceutically relevant targets. New technologies that offer methodology for the rapid generation of more structurally diverse libraries have now been demonstrated.

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Year:  2001        PMID: 11282342     DOI: 10.1016/s1367-5931(00)00185-x

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  15 in total

Review 1.  Combinatorial biosynthesis--potential and problems.

Authors:  Heinz G Floss
Journal:  J Biotechnol       Date:  2006-01-18       Impact factor: 3.307

Review 2.  Nonribosomal peptide synthetases involved in the production of medically relevant natural products.

Authors:  Elizabeth A Felnagle; Emily E Jackson; Yolande A Chan; Angela M Podevels; Andrew D Berti; Matthew D McMahon; Michael G Thomas
Journal:  Mol Pharm       Date:  2008-01-25       Impact factor: 4.939

3.  Sequence, cloning, and analysis of the fluvirucin B1 polyketide synthase from Actinomadura vulgaris.

Authors:  Tsung-Yi Lin; Lawrence S Borketey; Gitanjeli Prasad; Stephanie A Waters; Nathan A Schnarr
Journal:  ACS Synth Biol       Date:  2013-04-16       Impact factor: 5.110

Review 4.  Advancement in bioprocess technology: parallels between microbial natural products and cell culture biologics.

Authors:  Arpan A Bandyopadhyay; Anurag Khetan; Li-Hong Malmberg; Weichang Zhou; Wei-Shou Hu
Journal:  J Ind Microbiol Biotechnol       Date:  2017-02-09       Impact factor: 3.346

5.  A mechanism-based fluorescence transfer assay for examining ketosynthase selectivity.

Authors:  Gitanjeli Prasad; Lawrence S Borketey; Tsung-Yi Lin; Nathan A Schnarr
Journal:  Org Biomol Chem       Date:  2012-07-18       Impact factor: 3.876

6.  The crystal structure and mechanism of an unusual oxidoreductase, GilR, involved in gilvocarcin V biosynthesis.

Authors:  Nicholas Noinaj; Mary A Bosserman; M Alexandra Schickli; Grzegorz Piszczek; Madan K Kharel; Pallab Pahari; Susan K Buchanan; Jürgen Rohr
Journal:  J Biol Chem       Date:  2011-05-10       Impact factor: 5.157

7.  A C35 carotenoid biosynthetic pathway.

Authors:  Daisuke Umeno; Frances H Arnold
Journal:  Appl Environ Microbiol       Date:  2003-06       Impact factor: 4.792

8.  Solution structure and proposed domain domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase.

Authors:  Viktor Y Alekseyev; Corey W Liu; David E Cane; Joseph D Puglisi; Chaitan Khosla
Journal:  Protein Sci       Date:  2007-10       Impact factor: 6.725

9.  Genetic analysis of polyketide synthase and peptide synthetase genes in cyanobacteria as a mining tool for secondary metabolites.

Authors:  Martin E Barrios-Llerena; Adam M Burja; Phillip C Wright
Journal:  J Ind Microbiol Biotechnol       Date:  2007-04-25       Impact factor: 4.258

10.  Investigation of the biosynthetic potential of endophytes in traditional Chinese anticancer herbs.

Authors:  Kristin I Miller; Chen Qing; Daniel Man Yuen Sze; Brett A Neilan
Journal:  PLoS One       Date:  2012-05-22       Impact factor: 3.240

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