| Literature DB >> 11281992 |
Isabelle Seif1, Edward De Maeyer.
Abstract
A line of transgenic mice was isolated in which transgene integration had caused a deletion in the gene encoding monoamine oxidase A, an enzyme that degrades serotonin and norepinephrine. This has provided an animal model of MAOA deficiency in humans, a condition characterized by borderline mental retardation and impulsive aggression.Entities:
Year: 1999 PMID： 11281992 DOI： 10.1017/S1461145799001534
Source DB: PubMed Journal: Int J Neuropsychopharmacol ISSN： 1461-1457 Impact factor: 5.176