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Literature DB >> 11281806

An easy and convenient synthesis of Weinreb amides and hydroxamates.

L De Luca¹, G Giacomelli, M Taddei.

Abstract

Entities: Chemical

Year: 2001 PMID： 11281806 DOI： 10.1021/jo015524b

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

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12 in total

1. Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide.

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3. Novel endoperoxide-based transmission-blocking antimalarials with liver- and blood-schizontocidal activities.

Authors: Daniela Miranda; Rita Capela; Inês S Albuquerque; Patrícia Meireles; Isa Paiva; Fátima Nogueira; Richard Amewu; Jiri Gut; Philip J Rosenthal; Rudi Oliveira; Maria M Mota; Rui Moreira; Francesc Marti; Miguel Prudêncio; Paul M O'Neill; Francisca Lopes
Journal: ACS Med Chem Lett Date: 2013-12-20 Impact factor: 4.345

4. Synthetic studies of neoclerodane diterpenes from Salvia divinorum: role of the furan in affinity for opioid receptors.

Authors: Denise S Simpson; Kimberly M Lovell; Anthony Lozama; Nina Han; Victor W Day; Christina M Dersch; Richard B Rothman; Thomas E Prisinzano
Journal: Org Biomol Chem Date: 2009-07-14 Impact factor: 3.876

An easy and convenient synthesis of Weinreb amides and hydroxamates.

1. Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide.

2. Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties.

3. Novel endoperoxide-based transmission-blocking antimalarials with liver- and blood-schizontocidal activities.

4. Synthetic studies of neoclerodane diterpenes from Salvia divinorum: role of the furan in affinity for opioid receptors.

5. Fluorous 2,4-Dichloro-1,3,5-triazines (F-DCTs) as Nucleophile Scavengers.

6. Fluorous 2,4-Dichloro-1,3,5-triazine (F-DCT) as Amide Coupling Agent.

7. High-load, oligomeric dichlorotriazine: a versatile ROMP-derived reagent and scavenger.

8. Simple Synthesis of Amides and Weinreb Amides via Use of PPh₃ or Polymer-Supported PPh₃ and Iodine.

9. 16-Oxa-penta-cyclo-[6.6.5.0(1,18).0(2,7).0(9,14)]nona-deca-2,4,6,9,11,13,18-heptaen-15-one.

10. Naturally Inspired Peptide Leads: Alanine Scanning Reveals an Actin-Targeting Thiazole Analogue of Bisebromoamide.