Literature DB >> 1128175

Brain free fatty levels in rats sacrificed by decapitation versus focused microwave irradiation.

R J Cenedella, C Galli, R Paoletti.   

Abstract

Values are presented for whole brain free fatty acid levels of rats sacrificed by decapitation vs focused microwave irradiation. Free fatty acids were quantitated by specific colorimetric analysis. Within ca. 1 min of sacrifice by either decapitation or microwave, rat whole brain free fatty acid concentrations ranged from ca. 80-100 mug/g fresh tissue. If the brain remained in the head for a total of 5 min after decapitation, free fatty acid levels increased by over 100%. The free fatty acids at this time were enriched with arachidonic acid. The increase in free fatty acid levels following decapitation was completely absent in rats sacrificed by the microwave irradiation. This microwave technique could be a valuable tool in determining free fatty acid and other heat stable compounds in brain tissue.

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Year:  1975        PMID： 1128175     DOI： 10.1007/bf02532702

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  9 in total

1.  The colorimetric micro-determination of long-chain fatty acids.

Authors:  W G Duncombe
Journal:  Biochem J       Date:  1963-07       Impact factor: 3.857

2.  Regional distribution and rate of production of free fatty acids in rat brain.

Authors:  N G Bazan; H E de Bazan; W G Kennedy; C D Joel
Journal:  J Neurochem       Date:  1971-08       Impact factor: 5.372

3.  The production of unesterified fatty acid in brain.

Authors:  G G Lunt; C E Rowe
Journal:  Biochim Biophys Acta       Date:  1968-07-01

4.  Increased levels of brain free fatty acids after electroconvulsive shock.

Authors:  N G Bazan; H Rakowski
Journal:  Life Sci       Date:  1970-05-01       Impact factor: 5.037

5.  Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain.

Authors:  N G Bazán
Journal:  Biochim Biophys Acta       Date:  1970-10-06

6.  Brain lipid modifications induced by essential fatty acid deficiency in growing male and female rats.

Authors:  C Galli; H B White; R Paoletti
Journal:  J Neurochem       Date:  1970-03       Impact factor: 5.372

7.  Cerebroside galactosidase: a method for determination and a comparison with other lysosomal enzymes in developing rat brain.

Authors:  D M Bowen; N S Radin
Journal:  J Neurochem       Date:  1969-04       Impact factor: 5.372

8.  Hydrolase activities in brain of neurological mutants: cerebroside galactosidase, nitrophenyl galactoside hydrolase, nitrophenyl glucoside hydrolase and sulphatase.

Authors:  D M Bowen; N S Radin
Journal:  J Neurochem       Date:  1969-03       Impact factor: 5.372

9.  Lipid changes in rat brain during maturation.

Authors:  C Galli; D R Cecconi
Journal:  Lipids       Date:  1967-01       Impact factor: 1.880
  9 in total
  16 in total

Review 1.  Excitable membranes, lipid messengers, and immediate-early genes. Alteration of signal transduction in neuromodulation and neurotrauma.

Authors:  J P Doucet; N G Bazan
Journal:  Mol Neurobiol       Date:  1992       Impact factor: 5.590

Review 2.  Platelet-activating factor and polyunsaturated fatty acids in cerebral ischemia or convulsions: intracellular PAF-binding sites and activation of a fos/jun/AP-1 transcriptional signaling system.

Authors:  N G Bazan; S P Squinto; P Braquet; T Panetta; V L Marcheselli
Journal:  Lipids       Date:  1991-12       Impact factor: 1.880

Review 3.  Quantification of brain endocannabinoid levels: methods, interpretations and pitfalls.

Authors:  Matthew W Buczynski; Loren H Parsons
Journal:  Br J Pharmacol       Date:  2010-06       Impact factor: 8.739

4.  Effects of postdecapitation ischemia on the metabolism of [14C]arachidonic acid and [14C]palmitic acid in the mouse brain.

Authors:  M F Pediconi; E B Rodriguez de Turco; N G Bazan
Journal:  Neurochem Res       Date:  1983-07       Impact factor: 3.996

5.  Digitonide precipitable sterols: a reevaluation with special attention to lanosterol.

Authors:  R J Cenedella
Journal:  Lipids       Date:  1982-06       Impact factor: 1.880

6.  Concurrent measurement of (Na+, K+)-ATPase activity and lipid peroxides in rat brain following reversible global ischemia.

Authors:  W J Goldberg; B D Watson; R Busto; H Kurchner; M Santiso; M D Ginsberg
Journal:  Neurochem Res       Date:  1984-12       Impact factor: 3.996

7.  Effects of acute hypoxia on incorporation of [1-14C]arachidonic into glycerolipids of rat brain.

Authors:  J Strosznajder; G Y Sun
Journal:  Neurochem Res       Date:  1981-07       Impact factor: 3.996

8.  Effect of cytidine diphosphate choline (CDP-choline) on ischemia-induced alterations of brain lipid in the gerbil.

Authors:  G Trovarelli; G E de Medio; R V Dorman; G L Piccinin; L A Horrocks; G Porcellati
Journal:  Neurochem Res       Date:  1981-08       Impact factor: 3.996

9.  Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain.

Authors:  Santiago E Farias; Mireille Basselin; Lisa Chang; Kim A Heidenreich; Stanley I Rapoport; Robert C Murphy
Journal:  J Lipid Res       Date:  2008-05-23       Impact factor: 5.922

10.  Brain 2-Arachidonoylglycerol Levels Are Dramatically and Rapidly Increased Under Acute Ischemia-Injury Which Is Prevented by Microwave Irradiation.

Authors:  Stephen A Brose; Svetlana A Golovko; Mikhail Y Golovko
Journal:  Lipids       Date:  2016-03-28       Impact factor: 1.880
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