Literature DB >> 11280929

Design and implementation of an introductory course for computer applications in molecular genetics. A case study.

S A Krawetz1, D D Womble.   

Abstract

Formal training in computational biology was initiated at Wayne State University in 1990 to meet the needs of the faculty. This was still at a time when the molecular databases and analysis tools could be housed in what is now equivalent to a modern but dated desktop computer. In 1995 the course was expanded to include graduate students to provide these senior students with a foundation in computational biology. This course has armed our students with a requisite set of basic skills that are necessary for a successful career in molecular genetics. It is now an integral component of the graduate program of the Center for Molecular Medicine and Genetics and our experiences in course delivery have been detailed (BioInformatics Methods and Protocols, S. Misener and S. A. Krawetz, eds., Humana Press, Totowa, NJ, 2000.). The course was expanded to a campus-wide unlimited enrollment program for the summer of 2000 to address the needs of our student body. In this review we present our experience with delivering a multidisciplinary campus-wide computational biology course to a new and widely diverse student body.

Mesh:

Year:  2001        PMID: 11280929     DOI: 10.1385/MB:17:1:27

Source DB:  PubMed          Journal:  Mol Biotechnol        ISSN: 1073-6085            Impact factor:   2.695


  8 in total

Review 1.  The Staden sequence analysis package.

Authors:  R Staden
Journal:  Mol Biotechnol       Date:  1996-06       Impact factor: 2.695

2.  Rapid and sensitive sequence comparison with FASTP and FASTA.

Authors:  W R Pearson
Journal:  Methods Enzymol       Date:  1990       Impact factor: 1.600

3.  Computer assisted promoter analysis of a human sperm specific nucleoprotein gene cluster.

Authors:  J E Nelson; S A Krawetz
Journal:  DNA Seq       Date:  1995

4.  TreeView: an application to display phylogenetic trees on personal computers.

Authors:  R D Page
Journal:  Comput Appl Biosci       Date:  1996-08

5.  CENSOR--a program for identification and elimination of repetitive elements from DNA sequences.

Authors:  J Jurka; P Klonowski; V Dagman; P Pelton
Journal:  Comput Chem       Date:  1996-03

Review 6.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

Authors:  S F Altschul; T L Madden; A A Schäffer; J Zhang; Z Zhang; W Miller; D J Lipman
Journal:  Nucleic Acids Res       Date:  1997-09-01       Impact factor: 16.971

7.  MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data.

Authors:  K Quandt; K Frech; H Karas; E Wingender; T Werner
Journal:  Nucleic Acids Res       Date:  1995-12-11       Impact factor: 16.971

8.  CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

Authors:  J D Thompson; D G Higgins; T J Gibson
Journal:  Nucleic Acids Res       Date:  1994-11-11       Impact factor: 16.971

  8 in total
  3 in total

1.  Identification of rare paired box 3 variant in strabismus by whole exome sequencing.

Authors:  Hui-Min Gong; Jing Wang; Jing Xu; Zhan-Yu Zhou; Jing-Wen Li; Shu-Fang Chen
Journal:  Int J Ophthalmol       Date:  2017-08-18       Impact factor: 1.779

2.  Modulation of LXR-α and the effector genes by Ascorbic acid and Statins in psoriatic keratinocytes.

Authors:  Deepti Soodgupta; Deepak Kaul; A J Kanwar; Davinder Parsad
Journal:  Mol Cell Biochem       Date:  2014-10-05       Impact factor: 3.396

3.  Development of an undergraduate bioinformatics degree program at a liberal arts college.

Authors:  Paramjeet S Bagga
Journal:  Yale J Biol Med       Date:  2012-09-25
  3 in total

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