Literature DB >> 11277761

Microbial transformation of hypoestenone.

K A El Sayed1.   

Abstract

Preparative-scale fermentation of hypoestenone (1) with Mucor ramannianus (ATCC 9628) has resulted in the isolation of 8(9)alpha-epoxyhypoestenone (2) and the new metabolites 8(9)alpha-epoxy-12,13-anhydrohypoestenone (3), 17-hydroxyhypoestenone (4), 13alpha,18-dihydroxyhypoestenone (5), and 13beta,18-dihydroxyhypoestenone (6). Structure elucidation of these metabolites was based primarily on 1D and 2D NMR analyses.

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Year:  2001        PMID: 11277761     DOI: 10.1021/np0005255

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  1 in total

1.  A new terpene coumarin microbial transformed by Mucor polymorphosporus induces apoptosis of human gastric cancer cell line MGC-803.

Authors:  Guangzhi Li; Junchi Wang; Xiaojin Li; Jianguo Xu; Zhao Zhang; Jianyong Si
Journal:  Arch Pharm Res       Date:  2018-04-04       Impact factor: 4.946

  1 in total

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