BACKGROUND: An aggressive angiomyxoma of the pelvis is a locally infiltrative lesion treated with wide local excision. Recurrence is common. A potential medical treatment alternative is reported. CASE: A 34-year-old woman presented with her second recurrence of a vulvar angiomyxoma following two prior surgical excisions. Analysis of the recurrent tumor for estrogen and progesterone receptors was strongly positive. The patient was treated with 3 months of a gonadotropin-releasing hormone (GnRH) agonist. Comparison of pre- and posttreatment magnetic resonance imaging scans showed complete radiographic resolution of the tumor. Physical examination confirmed these findings. CONCLUSION: Medical management with a GnRH agonist may obviate the need for radical exenterative surgery for a recurrent aggressive angiomyxoma of the vulva. Copyright 2001 Academic Press.
BACKGROUND: An aggressive angiomyxoma of the pelvis is a locally infiltrative lesion treated with wide local excision. Recurrence is common. A potential medical treatment alternative is reported. CASE: A 34-year-old woman presented with her second recurrence of a vulvar angiomyxoma following two prior surgical excisions. Analysis of the recurrent tumor for estrogen and progesterone receptors was strongly positive. The patient was treated with 3 months of a gonadotropin-releasing hormone (GnRH) agonist. Comparison of pre- and posttreatment magnetic resonance imaging scans showed complete radiographic resolution of the tumor. Physical examination confirmed these findings. CONCLUSION: Medical management with a GnRH agonist may obviate the need for radical exenterative surgery for a recurrent aggressive angiomyxoma of the vulva. Copyright 2001 Academic Press.
Authors: Giovanni Fucà; Nadia Hindi; Isabelle Ray-Coquard; Vittoria Colia; Angelo Paolo Dei Tos; Javier Martin-Broto; Mehdi Brahmi; Paola Collini; Domenica Lorusso; Francesco Raspagliesi; Maria Abbondanza Pantaleo; Bruno Vincenzi; Elena Fumagalli; Alessandro Gronchi; Paolo Giovanni Casali; Roberta Sanfilippo Journal: Oncologist Date: 2018-12-05
Authors: Nivedita Sharma; Than Singh Tomar; Arun Peter Mathew; K Chandramohan; R Preethi; Rari P Mony Journal: Indian J Surg Date: 2017-06-04 Impact factor: 0.656