Literature DB >> 1127730

Inhibitory effect of interferon on multiplication of Friend leukemia cells in vivo.

G B Rossi, M Marchegiani, G P Matarese, I Gresser.   

Abstract

The multiplication of Friend leukemia cells in the spleens of irradiated or nonirradiated histocompatible DBA/2 mice was determined by the uptake of 125-5-iodo-2'-deoxyuridine. The multiplication was inhibited by daily treatment with mouse interferon preparations or the interferon inducer, Newcastle disease virus. Since, under the experimental conditions used, the proliferation of the Friend leukemia cells was independent of the replication of the Friend virus, the inhibitory effect of interferon might not be mediated by an antiviral effect but by some other mechanism.

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Year:  1975        PMID： 1127730

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  2 in total

1.  Inhibition of transcription and translation of globin messenger RNA in dimethyl sulfoxide-stimulated Friend erythroleukemic cells treated with interferon.

Authors:  G B Rossi; A Dolei; L Cioé; A Benedetto; G P Matarese; F Belardelli
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

2.  Effect of interferon on growth and division cycle of Friend erythroleukemic murine cells in vitro.

Authors:  G P Matarese; G B Rossi
Journal:  J Cell Biol       Date:  1977-11       Impact factor: 10.539
  2 in total

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