Literature DB >> 11274829

Bioactive chemical constituents from Alchornea laxiflora (benth) pax and hoffman.

O O Ogundipe1, J O Moody, P J Houghton, H A Odelola.   

Abstract

Quercetin-7,4'-disulphate (1) quercetin (2) quercetin-3',4'-disulphate (3) quercetin-3,4'-diacetate (4) rutin (5) and quercetrin (6) were isolated from the ethyl acetate soluble fraction (ESM) of the crude methanolic leaf extract of Alchornea laxiflora. Purification of these compounds was carried out by column chromatography utilising sephadex LH 20 and various mixtures of water, methanol, ethanol and toluene as eluents. Structural elucidation was by UV, IR, (1)HNMR and (13)CNMR spectroscopy as well as by FAB-MS. Antimicrobial activity of isolated compounds was detected in Gram-positive, Gram-negative and fungal organisms.

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Year:  2001        PMID： 11274829     DOI： 10.1016/s0378-8741(00)00352-4

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  5 in total

1.  Isolation and Characterisation of Quercitrin as a Potent Anti-Sickle Cell Anaemia Agent from Alchornea cordifolia.

Authors:  Olayemi Adeniyi; Rafael Baptista; Sumana Bhowmick; Alan Cookson; Robert J Nash; Ana Winters; Jianying Shen; Luis A J Mur
Journal:  J Clin Med       Date:  2022-04-13       Impact factor: 4.964

2.  Evaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffman.

Authors:  David A Akinpelu; Emmanuel O Abioye; Olayinka A Aiyegoro; Oluseun F Akinpelu; Anthony I Okoh
Journal:  Evid Based Complement Alternat Med       Date:  2015-01-19       Impact factor: 2.629

3.  Cytotoxicity of methanol extracts of 10 Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines.

Authors:  Victor Kuete; Cedric F Tchinda; Flora T Mambe; Veronique P Beng; Thomas Efferth
Journal:  BMC Complement Altern Med       Date:  2016-08-02       Impact factor: 3.659

4.  Antibacterial activities of the methanol extracts of Albizia adianthifolia, Alchornea laxiflora, Laportea ovalifolia and three other Cameroonian plants against multi-drug resistant Gram-negative bacteria.

Authors:  Cedric F Tchinda; Igor K Voukeng; Veronique P Beng; Victor Kuete
Journal:  Saudi J Biol Sci       Date:  2016-01-25       Impact factor: 4.219

5.  Antimalarial, antiplasmodial and analgesic activities of root extract of Alchornea laxiflora.

Authors:  Jude E Okokon; Nkemnele Bensella Augustine; Dinesh Mohanakrishnan
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503
  5 in total

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