Literature DB >> 1127384

Nonallelic behavior of rabbit variable-region allotypes.

M Mudgett, B A Fraser, T J Kindt.   

Abstract

Group a allotypes not detected by qualitative typing or anticipated from breeding data (latent allotypes) were detected at low levels in 50% of normal rabbit sera tested. The latent allotypes, which were serologically identical to allotypes of pooled IgG, were detected in sera from rabbits with all possible combinations of group a allotypes and their occurrence in individual rabbits was transitory and sporadic. These findings give reason to question the assumption that the synthesis of immunoglobulin allotypes is directed by allelic structural genes.

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Year:  1975        PMID: 1127384      PMCID: PMC2189849          DOI: 10.1084/jem.141.6.1448

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  9 in total

1.  Quantitative determination of allotypic and idiotypic markers with antisera coupled to N-hydroxysuccinimide-activated sepharose.

Authors:  A B Gottlieb; R K Seide; T J Kindt
Journal:  J Immunol       Date:  1975-01       Impact factor: 5.422

2.  A rabbit with the allotypic phenotype: ala2a3 b4b5b6.

Authors:  A D Strosberg; C Hamers-Casterman; W Van der Loo; R Hamers
Journal:  J Immunol       Date:  1974-10       Impact factor: 5.422

Review 3.  Human immunoglobulins: classes, subclasses, genetic variants, and idiotypes.

Authors:  J B Natvig; H G Kunkel
Journal:  Adv Immunol       Date:  1973       Impact factor: 3.543

4.  Immunoglobulin allotypic specificities in mixed leucocyte cultures.

Authors:  L Rivat; D Gilbert; C Ropartz
Journal:  Immunology       Date:  1973-06       Impact factor: 7.397

5.  Identification and genetic control of the f4 and f5 rabbit gamma-A immunoglobulin allotypes. Phenogroups at the f locus.

Authors:  T P Conway; S Dray; E A Lichter
Journal:  J Immunol       Date:  1969-10       Impact factor: 5.422

6.  A simplification of the radioactive antigen-binding test by a double label technique.

Authors:  E C Gotschlich
Journal:  J Immunol       Date:  1971-09       Impact factor: 5.422

7.  Expression of IgG allotypes in human lymphoid tumor lines serially transplantable in the neonatal Syrian hamster.

Authors:  L Pothier; H Borel; R A Adams
Journal:  J Immunol       Date:  1974-12       Impact factor: 5.422

8.  Detection of idiotypic cross-reactions among streptococcal antisera from related rabbits.

Authors:  T J Kindt; R K Seide; V A Bokisch; R M Krause
Journal:  J Exp Med       Date:  1973-09-01       Impact factor: 14.307

9.  Congenic mouse strains: the expression of a hidden immunoglobulin allotype in a congenic partner strain of BALB-c mice.

Authors:  M J Bosma; G C Bosma
Journal:  J Exp Med       Date:  1974-03-01       Impact factor: 14.307

  9 in total
  16 in total

1.  Recombination, mutation, or constitutive expression at a Gm locus and familial hypergammaglobulinemia.

Authors:  G Lefranc; L Rivat; J P Salier; E van Loghem; H Aydenian; P Zalzal; L Chakhachiro; J Loiselet; C Ropartz
Journal:  Am J Hum Genet       Date:  1977-09       Impact factor: 11.025

2.  The genetic control of the immune response to staphylococcal nuclease VI. Recombination between genes determining the A/J anti-nuclease idiotypes and the heavy chain allotype locus.

Authors:  D S Pisetsky; D H Sachs
Journal:  J Exp Med       Date:  1977-12-01       Impact factor: 14.307

3.  Immunoglobulin allotypes of rabbit kappa chains: polymorphism of a control mechanism regulating closely linked duplicated genes?

Authors:  V Farnsworth; R Goodfliesh; S Rodkey; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1976-04       Impact factor: 11.205

4.  Heavy chain genes of rabbit IgG: isolation of a cDNA encoding gamma heavy chain and identification of two genomic C gamma genes.

Authors:  C L Martens; K W Moore; M Steinmetz; L Hood; K L Knight
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

5.  Rabbit latent allotypes: current status and future directions.

Authors:  K H Roux
Journal:  Surv Immunol Res       Date:  1983

6.  Interallelic and intergenic conversion events could induce differential evolution of the two rabbit immunoglobulin kappa light chain genes.

Authors:  B Mariame; M A Akimenko; F Rougeon
Journal:  Nucleic Acids Res       Date:  1987-08-11       Impact factor: 16.971

7.  Structure and regulation of immunoglobulins: kappa allotypes in the rat have multiple amino-acid differences in the constant region.

Authors:  G A Gutman; E Loh; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

8.  Cosuppression of latent and nominal allotypes in individual rabbit lymphocytes.

Authors:  B Wolf; M L Yarmush
Journal:  Immunology       Date:  1985-05       Impact factor: 7.397

9.  Rabbit heavy chain haplotypes--allotypic determinants expressed by VH-CH recombinants.

Authors:  R G Mage; S Dray; A Gilman-Sachs; C Hamers-Casterman; R Hamers; W C Hanly; T J Kindt; K L Knight; W J Mandy; J Naessens
Journal:  Immunogenetics       Date:  1982-03       Impact factor: 2.846

10.  Genetic control of the immune response to nuclease. V. Genetic linkage and strain distribution of anti-nuclease idiotypes.

Authors:  C G Fathman; D S Pisetsky; D H Sachs
Journal:  J Exp Med       Date:  1977-03-01       Impact factor: 14.307

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