| Literature DB >> 11270615 |
H Fujiwara1, Y Eizuru, T Matsumoto, T Kukita, R Imaizumi, H Kawada, H Ohtsubo, K Matsushita, N Arima, C Tei.
Abstract
The significance of cytomegalovirus (CMV) infections developed over the clinical course of adult T-cell leukemia/lymphoma (ATLL) were evaluated in relation to the patient survival rate, ATL activity and immunocompetent cells. ATLL patients with CMV infections on admission exhibited a poor survival rate, while patients with CMV infections at any time after admission survived longer than those not infected with this virus. ATLL patients who exhibited a numbers of CMV infection on admission showed higher ATL activity and had lower numbers of CD8-positive and CD56-positive cells than those who developed CMV infections at any time after admission. Therefore, it appears likely that patients with CMV infections on admission were in an immunosuppressive state due to aggressive ATL activity.Entities:
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Year: 2001 PMID： 11270615 DOI： 10.1111/j.1348-0421.2001.tb01265.x
Source DB: PubMed Journal: Microbiol Immunol ISSN： 0385-5600 Impact factor: 1.955