Literature DB >> 11270252

[Acute myelitis of an unusual cause in a child: the lymphocytic choriomeningitis virus].

V Humbertclaude1, S Tourtet, M Semprino, A Roubertie, F Rivier, N Leboucq, J Astruc, B Echenne.   

Abstract

UNLABELLED: Acute transverse myelitis is a rare disorder in childhood. It usually occurs as a post-infectious disease, but a precise infectious agent is identified in only 20% of cases. OBSERVATION: The diagnosis of acute transverse myelitis was made in a 5.5-year-old girl who initially presented with left Claude-Bernard-Horner syndrome and meningitis. A few days later, motor and sensory tetraparesia with bladder dysfunction was observed. Magnetic resonance imaging showed a diffuse lesion in the medulla, with a hypersignal in the T2 and a hyposignal in the T1 sequences. Serum analysis showed the presence of a viral infection due to the lymphocytic choriomeningitis (LCM) virus. The outcome was marked by complete recovery of the sensorimotor deficit, but a persistence of the left Claude-Bernard-Horner syndrome.
CONCLUSION: In rare cases, the LCM virus is responsible for myelitis. In the present case, the Claude-Bernard-Horner syndrome was secondary to the cervico-medullary lesion. Recent reports in the literature have been discussed, in particular as regards the use of immunomodulatory therapy, which clearly improves patient prognosis.

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Year:  2001        PMID: 11270252     DOI: 10.1016/s0929-693x(00)00196-2

Source DB:  PubMed          Journal:  Arch Pediatr        ISSN: 0929-693X            Impact factor:   1.180


  2 in total

1.  Distinct neural stem cell tropism, early immune activation, and choroid plexus pathology following coxsackievirus infection in the neonatal central nervous system.

Authors:  Jenna M Puccini; Chelsea M Ruller; Scott M Robinson; Kristeene A Knopp; Michael J Buchmeier; Kelly S Doran; Ralph Feuer
Journal:  Lab Invest       Date:  2013-12-30       Impact factor: 5.662

2.  Prevalence and Risk Factors for Lymphocytic Choriomeningitis Virus Infection in Continental Croatian Regions.

Authors:  Tatjana Vilibic-Cavlek; Tena Oreski; Misa Korva; Branko Kolaric; Vladimir Stevanovic; Snjezana Zidovec-Lepej; Irena Tabain; Pavle Jelicic; Bozana Miklausic-Pavic; Vladimir Savic; Ljubo Barbic; Tatjana Avsic-Zupanc
Journal:  Trop Med Infect Dis       Date:  2021-04-29
  2 in total

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