Literature DB >> 11267677

Molecular cloning of a cDNA for rat TM4SF4, a homolog of human il-TMP (TM4SF4), and enhanced expression of the corresponding gene in regenerating rat liver(1).

Z Liu1, M Zhao, K K Yokoyama, T Li.   

Abstract

il-TMP (also known as TM4SF4) is a human tetraspanin that is expressed in human intestine and liver. We have cloned a novel cDNA for a rat gene with sequence similar to that of a cDNA for human il-TMP. The cDNA encoded a protein of 202 amino acids, designated rat TM4SF4. The corresponding transcript was detected in rat liver and testis. The expression of rat TM4SF4 was enhanced in regenerating liver after two-thirds partial hepatectomy. It was supposed that rat TM4SF4 might play a role in cell proliferation and in liver regeneration.

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Year:  2001        PMID： 11267677     DOI： 10.1016/s0167-4781(01)00170-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  6 in total

1.  The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration.

Authors:  Keith R Anderson; Ruth A Singer; Dina A Balderes; Laura Hernandez-Lagunas; Christopher W Johnson; Kristin B Artinger; Lori Sussel
Journal:  Development       Date:  2011-08       Impact factor: 6.868

2.  Association of TM4SF4 with the human thiamine transporter-2 in intestinal epithelial cells.

Authors:  Veedamali S Subramanian; Svetlana M Nabokina; Hamid M Said
Journal:  Dig Dis Sci       Date:  2013-11-27       Impact factor: 3.199

3.  TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1.

Authors:  Soo-Im Choi; Seo-Yeon Kim; Jaeha Lee; Eun-Wie Cho; In-Gyu Kim
Journal:  Oncotarget       Date:  2014-10-30

4.  Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells.

Authors:  Soo Im Choi; Seo Yoen Kim; Jei Ha Lee; Jung Yul Kim; Eun Wie Cho; In-Gyu Kim
Journal:  Oncotarget       Date:  2017-09-18

5.  Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment.

Authors:  Jin-Gyu Cheong; Dae-Geun Song; Haeng Eun Song; Fedor Berditchevski; Seo Hee Nam; Jae Woo Jung; Hye-Jin Kim; Ji Eon Kim; Somi Kim; Jihye Ryu; Chang Yun Cho; Kyung-Min Lee; Jung Weon Lee
Journal:  Oncotarget       Date:  2017-02-21

6.  RNA-Seq reveals dynamic changes of gene expression in key stages of intestine regeneration in the sea cucumber Apostichopus japonicus. [corrected].

Authors:  Lina Sun; Hongsheng Yang; Muyan Chen; Deyou Ma; Chenggang Lin
Journal:  PLoS One       Date:  2013-08-06       Impact factor: 3.240
  6 in total

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