Literature DB >> 11267673

Molecular cloning, mapping and characterization of the human neurocalcin delta gene (NCALD).

W Wang1, Z Zhou, W Zhao, Y Huang, R Tang, K Ying, Y Xie, Y Mao.   

Abstract

We identified a new human gene that encodes a cognate of the bovine neurocalcin delta from a human fetal brain cDNA library; hence we named it human neurocalcin delta (NCALD) gene. The deduced polypeptide product of the cDNA is 22 kDa in size, and its amino acid sequence is 100% and 99% identical to that of the bovine and chicken neurocalcin, respectively. Northern blots showed that the NCALD gene is more abundantly expressed in brain, testis, ovary and small intestine. Tissue in situ hybridization confirmed the existence of the NCALD mRNA in the adult human testis. Radiation hybrid panel mapping localized the gene to chromosome 8 between molecular markers D8S270 and D8S257.

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Year:  2001        PMID： 11267673     DOI： 10.1016/s0167-4781(00)00290-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.

Authors:  Masumi Kamiyama; Masaaki Kobayashi; Shin-ichi Araki; Aritoshi Iida; Tatsuhiko Tsunoda; Koichi Kawai; Masahito Imanishi; Makoto Nomura; Tetsuya Babazono; Yasuhiko Iwamoto; Atsunori Kashiwagi; Kohei Kaku; Ryuzou Kawamori; Daniel P K Ng; Torben Hansen; Peter Gaede; Oluf Pedersen; Yusuke Nakamura; Shiro Maeda
Journal:  Hum Genet       Date:  2007-08-02       Impact factor: 4.132

2.  Neurocalcin Delta Knockout Impairs Adult Neurogenesis Whereas Half Reduction Is Not Pathological.

Authors:  Aaradhita Upadhyay; Seyyedmohsen Hosseinibarkooie; Svenja Schneider; Anna Kaczmarek; Laura Torres-Benito; Natalia Mendoza-Ferreira; Melina Overhoff; Roman Rombo; Vanessa Grysko; Min Jeong Kye; Natalia L Kononenko; Brunhilde Wirth
Journal:  Front Mol Neurosci       Date:  2019-02-12       Impact factor: 5.639

3.  High NCALD expression predicts poor prognosis of cytogenetic normal acute myeloid leukemia.

Authors:  Ying Song; Weilong Zhang; Xue He; Xiaoni Liu; Ping Yang; Jing Wang; Kai Hu; Weiyou Liu; Xiuru Zhang; Hongmei Jing; Xiaoliang Yuan
Journal:  J Transl Med       Date:  2019-05-20       Impact factor: 5.531

4.  Helicid Reverses the Effect of Overexpressing NCALD, Which Blocks the sGC/cGMP/PKG Signaling Pathway in the CUMS-Induced Rat Model.

Authors:  Xiao-Tong Zhang; Yuan Zhang; Yuan-Xiang Zhang; Zhen-Yi Jiang; Hui Yang; Lan Jiang; Bin Yang; Jiu-Cui Tong
Journal:  J Healthc Eng       Date:  2021-12-11       Impact factor: 2.682

5.  Congruence of tissue expression profiles from Gene Expression Atlas, SAGEmap and TissueInfo databases.

Authors:  Lukasz Huminiecki; Andrew T Lloyd; Kenneth H Wolfe
Journal:  BMC Genomics       Date:  2003-07-29       Impact factor: 3.969

6.  Whole genome expression profiling of blood cells in ovarian cancer patients -prognostic impact of the CYP1B1, MTSS1, NCALD, and NOP14.

Authors:  Helena S Isaksson; Bengt Sorbe; Torbjörn K Nilsson
Journal:  Oncotarget       Date:  2014-06-30

7.  Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer.

Authors:  Xuefei Shi; Chenhui Ma; Qingqing Zhu; Dongmei Yuan; Ming Sun; Xiaoling Gu; Guannan Wu; Tangfeng Lv; Yong Song
Journal:  Oncotarget       Date:  2016-05-03

8.  Clinicopathological and prognostic significance of NCALD protein expression in lung adenocarcinoma.

Authors:  Yi Chen; Xueren Feng; Hui Shen; Lijuan Zhang; Xiaoyong Li; Liliang Gao; Xiaohuo Zhang; Bin Wang
Journal:  Transl Cancer Res       Date:  2019-06       Impact factor: 1.241
  8 in total

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