| Literature DB >> 11266183 |
H Juteau1, Y Gareau, M Labelle, S Lamontagne, N Tremblay, M C Carrière, N Sawyer, D Denis, K M Metters.
Abstract
Potent and selective EP3 receptor ligands were found by making a library using solid-support chemistry. These compounds can be obtained by a Suzuki coupling reaction of a solid-supported benzyl bromide using various boronic acids. The yields obtained for this reaction were in the range of 24-95% of arylmethyl cinnamic acid 1 after cleavage from the Wang resin.Entities:
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Year: 2001 PMID： 11266183 DOI： 10.1016/s0960-894x(01)00056-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823