| Literature DB >> 11266160 |
J M Fevig1, D J Pinto, Q Han, M L Quan, J R Pruitt, I C Jacobson, R A Galemmo, S Wang, M J Orwat, L L Bostrom, R M Knabb, P C Wong, R R Wexler.
Abstract
The selective inhibition of coagulation factor Xa has emerged as an attractive strategy for the discovery of novel antithrombotic agents. Here we describe highly potent benzamidine factor Xa inhibitors based on a vicinally-substituted heterocyclic core.Entities:
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Year: 2001 PMID： 11266160 DOI： 10.1016/s0960-894x(01)00029-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823