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Literature DB >> 11265279

Assays for the evaluation of HIV-1 integrase inhibitors.

Z Debyser¹, P Cherepanov, W Pluymers, E De Clercq.

Abstract

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Year: 2001 PMID： 11265279 DOI： 10.1385/1-59259-233-3:139

Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745

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10 in total

Review 1. Authentic HIV-1 integrase inhibitors.

Authors: Chenzhong Liao; Christophe Marchand; Terrence R Burke; Yves Pommier; Marc C Nicklaus
Journal: Future Med Chem Date: 2010-07 Impact factor: 3.808

2. The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import.

Authors: Stéphanie De Houwer; Jonas Demeulemeester; Wannes Thys; Susana Rocha; Lieve Dirix; Rik Gijsbers; Frauke Christ; Zeger Debyser
Journal: J Biol Chem Date: 2014-07-25 Impact factor: 5.157

3. Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations.

Authors: Valery Fikkert; Bénédicte Van Maele; Jo Vercammen; Anke Hantson; Barbara Van Remoortel; Martine Michiels; Cristina Gurnari; Christophe Pannecouque; Marc De Maeyer; Yves Engelborghs; Erik De Clercq; Zeger Debyser; Myriam Witvrouw
Journal: J Virol Date: 2003-11 Impact factor: 5.103

4. Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137.

Authors: Anneleen Hombrouck; Arnout Voet; Barbara Van Remoortel; Christel Desadeleer; Marc De Maeyer; Zeger Debyser; Myriam Witvrouw
Journal: Antimicrob Agents Chemother Date: 2008-03-31 Impact factor: 5.191

Review 5. HIV-1 IN inhibitors: 2010 update and perspectives.

Authors: Christophe Marchand; Kasthuraiah Maddali; Mathieu Métifiot; Yves Pommier
Journal: Curr Top Med Chem Date: 2009 Impact factor: 3.295

6. Novel 3'-Processing Integrase Activity Assay by Real-Time PCR for Screening and Identification of HIV-1 Integrase Inhibitors.

Authors: Supachai Sakkhachornphop; Weeraya Thongkum; Chatchai Tayapiwatana
Journal: Biomed Res Int Date: 2015-05-07 Impact factor: 3.411

Assays for the evaluation of HIV-1 integrase inhibitors.

Review 1. Authentic HIV-1 integrase inhibitors.

2. The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import.

3. Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations.

4. Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137.

Review 5. HIV-1 IN inhibitors: 2010 update and perspectives.

6. Novel 3'-Processing Integrase Activity Assay by Real-Time PCR for Screening and Identification of HIV-1 Integrase Inhibitors.

7. A time-of-drug addition approach to target identification of antiviral compounds.

8. Comparative biochemical analysis of HIV-1 subtype B and C integrase enzymes.

9. Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives.

10. Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.