Literature DB >> 11265250

SUMO, ubiquitin's mysterious cousin.

S Müller1, C Hoege, G Pyrowolakis, S Jentsch.   

Abstract

Covalent modification of cellular proteins by the ubiquitin-like modifier SUMO regulates various cellular processes, such as nuclear transport, signal transduction, stress response and cell-cycle progression. But, in contrast to ubiquitylation, sumoylation does not tag proteins for degradation, but seems to enhance their stability or modulate their subcellular compartmentalization.

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Year:  2001        PMID: 11265250     DOI: 10.1038/35056591

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  230 in total

1.  PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.

Authors:  S Sachdev; L Bruhn; H Sieber; A Pichler; F Melchior; R Grosschedl
Journal:  Genes Dev       Date:  2001-12-01       Impact factor: 11.361

2.  Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity.

Authors:  Darja Schmidt; Stefan Müller
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-26       Impact factor: 11.205

Review 3.  Modification with SUMO. A role in transcriptional regulation.

Authors:  Alexis Verger; José Perdomo; Merlin Crossley
Journal:  EMBO Rep       Date:  2003-02       Impact factor: 8.807

4.  Molecular characterization of mouse gastric epithelial progenitor cells.

Authors:  Jason C Mills; Niklas Andersson; Chieu V Hong; Thaddeus S Stappenbeck; Jeffrey I Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-30       Impact factor: 11.205

5.  S-adenosyl methionine regulates ubiquitin-conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers.

Authors:  Maria Lauda Tomasi; Ivan Tomasi; Komal Ramani; Rosa Maria Pascale; Jun Xu; Pasquale Giordano; José M Mato; Shelly C Lu
Journal:  Hepatology       Date:  2012-07-12       Impact factor: 17.425

6.  Histone sumoylation is associated with transcriptional repression.

Authors:  Yuzuru Shiio; Robert N Eisenman
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-24       Impact factor: 11.205

7.  PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

Authors:  Noora Kotaja; Ulla Karvonen; Olli A Jänne; Jorma J Palvimo
Journal:  Mol Cell Biol       Date:  2002-07       Impact factor: 4.272

8.  Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.

Authors:  Serge Grégoire; Xiang-Jiao Yang
Journal:  Mol Cell Biol       Date:  2005-03       Impact factor: 4.272

9.  A novel plant cysteine protease has a dual function as a regulator of 1-aminocyclopropane-1-carboxylic Acid synthase gene expression.

Authors:  Noa Matarasso; Silvia Schuster; Adi Avni
Journal:  Plant Cell       Date:  2005-03-04       Impact factor: 11.277

10.  SUMO-conjugating enzyme E2 UBC9 mediates viral immediate-early protein SUMOylation in crayfish to facilitate reproduction of white spot syndrome virus.

Authors:  An-Jing Chen; Lu Gao; Xian-Wei Wang; Xiao-Fan Zhao; Jin-Xing Wang
Journal:  J Virol       Date:  2012-10-24       Impact factor: 5.103

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