| Literature DB >> 11265250 |
S Müller1, C Hoege, G Pyrowolakis, S Jentsch.
Abstract
Covalent modification of cellular proteins by the ubiquitin-like modifier SUMO regulates various cellular processes, such as nuclear transport, signal transduction, stress response and cell-cycle progression. But, in contrast to ubiquitylation, sumoylation does not tag proteins for degradation, but seems to enhance their stability or modulate their subcellular compartmentalization.Mesh:
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Year: 2001 PMID: 11265250 DOI: 10.1038/35056591
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN: 1471-0072 Impact factor: 94.444