Literature DB >> 11265247

Antigen processing by the proteasome.

P M Kloetzel1.   

Abstract

The proteasome is an essential part of our immune surveillance mechanisms: by generating peptides from intracellular antigens it provides peptides that are then 'presented' to T cells. But proteasomes--the waste-disposal units of the cell--typically do not generate peptides for antigen presentation with high efficiency. How, then, does the proteasome adapt to serve the immune system well?

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Year:  2001        PMID： 11265247     DOI： 10.1038/35056572

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  190 in total

1.  Two antigenic peptides from genes m123 and m164 of murine cytomegalovirus quantitatively dominate CD8 T-cell memory in the H-2d haplotype.

Authors:  Rafaela Holtappels; Doris Thomas; Jürgen Podlech; Matthias J Reddehase
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103

2.  PI31 is a modulator of proteasome formation and antigen processing.

Authors:  Dietmar M W Zaiss; Sybille Standera; Peter-M Kloetzel; Alice J A M Sijts
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-08       Impact factor: 11.205

3.  Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome.

Authors:  Can Kesmir; Vera van Noort; Rob J de Boer; Paulien Hogeweg
Journal:  Immunogenetics       Date:  2003-08-30       Impact factor: 2.846

Review 4.  Getting into position: the catalytic mechanisms of protein ubiquitylation.

Authors:  Lori A Passmore; David Barford
Journal:  Biochem J       Date:  2004-05-01       Impact factor: 3.857

5.  Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules.

Authors:  Danielle de Verteuil; Tara L Muratore-Schroeder; Diana P Granados; Marie-Hélène Fortier; Marie-Pierre Hardy; Alexandre Bramoullé; Etienne Caron; Krystel Vincent; Sylvie Mader; Sébastien Lemieux; Pierre Thibault; Claude Perreault
Journal:  Mol Cell Proteomics       Date:  2010-05-19       Impact factor: 5.911

6.  Cell type-specific proteasomal processing of HIV-1 Gag-p24 results in an altered epitope repertoire.

Authors:  Nicholas J Steers; Jeffrey R Currier; Gustavo H Kijak; Robert C di Targiani; Ashima Saxena; Mary A Marovich; Jerome H Kim; Nelson L Michael; Carl R Alving; Mangala Rao
Journal:  J Virol       Date:  2010-11-24       Impact factor: 5.103

7.  T-cell recognition is shaped by epitope sequence conservation in the host proteome and microbiome.

Authors:  Anne Bresciani; Sinu Paul; Nina Schommer; Myles B Dillon; Tara Bancroft; Jason Greenbaum; Alessandro Sette; Morten Nielsen; Bjoern Peters
Journal:  Immunology       Date:  2016-02-08       Impact factor: 7.397

8.  PSMB5 plays a dual role in cancer development and immunosuppression.

Authors:  Chih-Yang Wang; Chung-Yen Li; Hui-Ping Hsu; Chien-Yu Cho; Meng-Chi Yen; Tzu-Yang Weng; Wei-Ching Chen; Yu-Hsuan Hung; Kuo-Ting Lee; Jui-Hsiang Hung; Yi-Ling Chen; Ming-Derg Lai
Journal:  Am J Cancer Res       Date:  2017-11-01       Impact factor: 6.166

9.  Neuronal induction of the immunoproteasome in Huntington's disease.

Authors:  Miguel Díaz-Hernández; Félix Hernández; Ester Martín-Aparicio; Pilar Gómez-Ramos; María A Morán; José G Castaño; Isidro Ferrer; Jesús Avila; José J Lucas
Journal:  J Neurosci       Date:  2003-12-17       Impact factor: 6.167

10.  Ongoing coxsackievirus myocarditis is associated with increased formation and activity of myocardial immunoproteasomes.

Authors:  Gudrun Szalay; Silke Meiners; Antje Voigt; Jörg Lauber; Christian Spieth; Nora Speer; Martina Sauter; Ulrike Kuckelkorn; Andreas Zell; Karin Klingel; Karl Stangl; Reinhard Kandolf
Journal:  Am J Pathol       Date:  2006-05       Impact factor: 4.307
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