BACKGROUND: Relative survival rates can offer a general description of tumor outcome and, traditionally, are used for surveillance and comparison purposes. However, they are not informative for individual tumor survivors. Conditional survival estimates can calculate the probability of surviving next some years given survival to a specific period of time after craniotomy for individual tumor survivors. However, clinically, they have not been used for predicting the tumor outcome. METHODS: We calculated conditional probabilities of survival within 6 years after craniotomy in 112 patients with primary supratentorial astrocytic tumors and evaluated factors affecting the survival time more than 2 years after craniotomy. RESULTS: Our data showed that the conditional probability of survival can predict yearly survival rate when patients survive for a specific period of time. The conditional survival rates within 6 years after craniotomy were always higher than those evaluated by relative survival rates. Overall, the longer the patients survived, the higher the conditional probabilities of surviving sixth year postoperatively were. CONCLUSION: Our study demonstrates the conditional probabilities of survival have good availability and are important estimates for individual tumor survivors.
BACKGROUND: Relative survival rates can offer a general description of tumor outcome and, traditionally, are used for surveillance and comparison purposes. However, they are not informative for individual tumor survivors. Conditional survival estimates can calculate the probability of surviving next some years given survival to a specific period of time after craniotomy for individual tumor survivors. However, clinically, they have not been used for predicting the tumor outcome. METHODS: We calculated conditional probabilities of survival within 6 years after craniotomy in 112 patients with primary supratentorial astrocytic tumors and evaluated factors affecting the survival time more than 2 years after craniotomy. RESULTS: Our data showed that the conditional probability of survival can predict yearly survival rate when patients survive for a specific period of time. The conditional survival rates within 6 years after craniotomy were always higher than those evaluated by relative survival rates. Overall, the longer the patients survived, the higher the conditional probabilities of surviving sixth year postoperatively were. CONCLUSION: Our study demonstrates the conditional probabilities of survival have good availability and are important estimates for individual tumor survivors.
Authors: S V Rajkumar; J C Buckner; P J Schomberg; J M Reid; P J Bagniewski; M M Ames; T L Cascino; R S Marks Journal: Int J Radiat Oncol Biol Phys Date: 1998-12-01 Impact factor: 7.038
Authors: P J Miller; R S Hassanein; P G Giri; B F Kimler; P O'Boynick; R G Evans Journal: Int J Radiat Oncol Biol Phys Date: 1990-08 Impact factor: 7.038
Authors: C Dazzi; A Cariello; M Giannini; M Del Duca; P Giovanis; G Fiorentini; M Leoni; G Rosti; D Turci; A Tienghi; B Vertogen; F Zumaglini; U De Giorgi; M Marangolo Journal: Anticancer Res Date: 2000 Jan-Feb Impact factor: 2.480
Authors: Samuel J Wang; Rachel Emery; Clifton D Fuller; Jong-Sung Kim; Dean F Sittig; Charles R Thomas Journal: Gastric Cancer Date: 2007-09-26 Impact factor: 7.370
Authors: Samuel J Wang; Amanda R Wissel; Join Y Luh; C David Fuller; Jayashree Kalpathy-Cramer; Charles R Thomas Journal: Ann Surg Oncol Date: 2011-01-05 Impact factor: 5.344
Authors: Mei-Yin C Polley; Kathleen R Lamborn; Susan M Chang; Nicholas Butowski; Jennifer L Clarke; Michael Prados Journal: J Clin Oncol Date: 2011-10-03 Impact factor: 44.544
Authors: Yan Xing; George J Chang; Chung-Yuan Hu; Robert L Askew; Merrick I Ross; Jeffrey E Gershenwald; Jeffrey E Lee; Paul F Mansfield; Anthony Lucci; Janice N Cormier Journal: Cancer Date: 2010-05-01 Impact factor: 6.860
Authors: Ann C Mertens; Jian Yong; Andrew C Dietz; Erin Kreiter; Yutaka Yasui; Archie Bleyer; Gregory T Armstrong; Leslie L Robison; Karen Wasilewski-Masker Journal: Cancer Date: 2014-12-29 Impact factor: 6.860
Authors: Beth A Zamboni; Greg Yothers; Mehee Choi; Clifton D Fuller; James J Dignam; Peter C Raich; Charles R Thomas; Michael J O'Connell; Norman Wolmark; Samuel J Wang Journal: J Clin Oncol Date: 2010-04-20 Impact factor: 44.544
Authors: Helen E Dinkelspiel; Miriam Champer; June Hou; Ana Tergas; William M Burke; Yongmei Huang; Alfred I Neugut; Cande V Ananth; Dawn L Hershman; Jason D Wright Journal: Gynecol Oncol Date: 2015-06-05 Impact factor: 5.482