Literature DB >> 11262966

Detecting gene relations from Medline abstracts.

M Stephens1, M Palakal, S Mukhopadhyay, R Raje, J Mostafa.   

Abstract

Research in bioinformatics in the past decade has generated a large volume of textual biological data stored in databases such as MEDLINE. It takes a copious amount of effort and time, even for expert users, to manually extract useful information embedded in such a large volume of retrieved data and automated intelligent text analysis tools are increasingly becoming essential. In this article, we present a simple analysis and knowledge discovery method that can identify related genes as well as their shared functionality (if any) based on a collection of relevant retrieved relevant MEDLINE documents. The relative computational simplicity of the proposed method makes it possible to process and analyze large volumes of data in a short time. Hence, it significantly contributes to and enhances a user's ability to discover such embedded information. Two case studies are presented that indicate the usefulness of the proposed method.

Mesh:

Year:  2001        PMID: 11262966     DOI: 10.1142/9789814447362_0047

Source DB:  PubMed          Journal:  Pac Symp Biocomput        ISSN: 2335-6928


  13 in total

1.  Associating genes with gene ontology codes using a maximum entropy analysis of biomedical literature.

Authors:  Soumya Raychaudhuri; Jeffrey T Chang; Patrick D Sutphin; Russ B Altman
Journal:  Genome Res       Date:  2002-01       Impact factor: 9.043

2.  Discovering protein similarity using natural language processing.

Authors:  Indra N Sarkar; Thomas C Rindflesch
Journal:  Proc AMIA Symp       Date:  2002

3.  NLP-based information extraction for managing the molecular biology literature.

Authors:  Bisharah Libbus; Thomas C Rindflesch
Journal:  Proc AMIA Symp       Date:  2002

4.  Research for research: tools for knowledge discovery and visualization.

Authors:  Erik M Van Mulligen; Christiaan Van Der Eijk; Jan A Kors; Bob J A Schijvenaars; Barend Mons
Journal:  Proc AMIA Symp       Date:  2002

5.  Using text analysis to identify functionally coherent gene groups.

Authors:  Soumya Raychaudhuri; Hinrich Schütze; Russ B Altman
Journal:  Genome Res       Date:  2002-10       Impact factor: 9.043

6.  Extraction of protein interaction data: a comparative analysis of methods in use.

Authors:  Hena Jose; Thangavel Vadivukarasi; Jyothi Devakumar
Journal:  EURASIP J Bioinform Syst Biol       Date:  2007

7.  Dynamic programming re-ranking for PPI interactor and pair extraction in full-text articles.

Authors:  Richard Tzong-Han Tsai; Po-Ting Lai
Journal:  BMC Bioinformatics       Date:  2011-02-23       Impact factor: 3.169

Review 8.  The Human Ageing Genomic Resources: online databases and tools for biogerontologists.

Authors:  João Pedro de Magalhães; Arie Budovsky; Gilad Lehmann; Joana Costa; Yang Li; Vadim Fraifeld; George M Church
Journal:  Aging Cell       Date:  2008-11-05       Impact factor: 9.304

9.  Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor stimulation.

Authors:  Rob Jelier; Guido Jenster; Lambert C J Dorssers; Bas J Wouters; Peter J M Hendriksen; Barend Mons; Ruud Delwel; Jan A Kors
Journal:  BMC Bioinformatics       Date:  2007-01-18       Impact factor: 3.169

10.  BBP: Brucella genome annotation with literature mining and curation.

Authors:  Zuoshuang Xiang; Wenjie Zheng; Yongqun He
Journal:  BMC Bioinformatics       Date:  2006-07-16       Impact factor: 3.169

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