Models of community treatments in schizophrenia: do they travel?

OBJECTIVE: To explore the stability of conclusions from mental health services research across differing care systems. Contradictory results in different countries for similar studies of programmes for patients with schizophrenia have usually been attributed to poor replication. This paper explores whether these differing results can illuminate aspects of schizophrenia by examining the interaction of the disorder with the care context as an alternative explanation.
METHOD: The findings of a large UK random controlled trial of intensive case management with such patients is compared to previous UK and US studies.
RESULTS: Reduction of case-load size of psychotic patients did not significantly reduce their need for hospitalization in the context of locally available co-ordinated care.
CONCLUSION: There is more to be gained in understanding complex disorders such as schizophrenia by interpreting the impact of context on treatment study outcomes than by simply dismissing contradictory findings as failures of implementation of either research or clinical practice.

RCT Entities:   Population Interventions Outcomes